Gene table of NTHL1 : nth like DNA glycosylase 1

Gene-disease associations table

Disease IDDisease nameSource of annotation with NTHL1OMIM linkNumber of associated genesgenes
PS175100FAMAILIAL ADENOMATOUS POLYPOSISClinVar, OMIM link to OMIM 3APC, MUTYH, NTHL1

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Annotation of the gene NTHL1

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Base excision repairhsa034107.6
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Displacement of DNA glycosylase by APEX1R-HSA-1103579.81
Cleavage of the damaged pyrimidine R-HSA-1103299.98
Recognition and association of DNA glycosylase with site containing an affected pyrimidineR-HSA-1103289.98
Resolution of Abasic Sites (AP sites)R-HSA-739337.85
DNA RepairR-HSA-738945.8
Base Excision RepairR-HSA-738847.85
DepyrimidinationR-HSA-739289.98
Base-Excision Repair, AP Site FormationR-HSA-739299.66
Associated GO terms for Molecular function
GO termGO IDGO IC
hydrolase activity, hydrolyzing N-glycosyl compoundsGO:00167996.6
hydrolase activity, acting on glycosyl bondsGO:00167984.91
bindingGO:00054880.18
nucleic acid bindingGO:00036761.44
DNA bindingGO:00036771.92
heterocyclic compound bindingGO:19013631.06
cation bindingGO:00431691.4
metal cluster bindingGO:00515405.55
oxidized pyrimidine nucleobase lesion DNA N-glycosylase activityGO:00007039.05
oxidized base lesion DNA N-glycosylase activityGO:00007028.64
endodeoxyribonuclease activityGO:00045205.81
ion bindingGO:00431671.36
double-stranded DNA bindingGO:00036903.09
metal ion bindingGO:00468721.41
hydrolase activityGO:00167871.9
DNA N-glycosylase activityGO:00191047.03
hydrolase activity, acting on ester bondsGO:00167883.1
DNA-(apurinic or apyrimidinic site) lyase activityGO:00039067.1
catalytic activityGO:00038241.05
4 iron, 4 sulfur cluster bindingGO:00515396.0
nuclease activityGO:00045184.33
carbon-oxygen lyase activityGO:00168355.46
iron-sulfur cluster bindingGO:00515365.55
oxidized purine nucleobase lesion DNA N-glycosylase activityGO:00085349.05
deoxyribonuclease activityGO:00045365.48
protein bindingGO:00055150.46
endonuclease activityGO:00045194.78
organic cyclic compound bindingGO:00971591.05
lyase activityGO:00168294.53