Gene table of NUDT15 : nudix hydrolase 15

Gene-disease associations table

Disease ID	Disease name	Source of annotation with NUDT15	OMIM link	Number of associated genes	genes
PS610460	THIOPURINES, POOR METABOLISM OF	ClinVar, OMIM	link to OMIM	2	NUDT15, TPMT

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Metabolism of nucleotides	R-HSA-15869	6.7
Metabolism	R-HSA-1430728	2.34
Phosphate bond hydrolysis by NUDT proteins	R-HSA-2393930	10.4

Associated GO terms for Molecular function

GO term	GO ID	GO IC
hydrolase activity	GO:0016787	1.9
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	GO:0016818	3.03
catalytic activity	GO:0003824	1.05
8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity	GO:0008413	9.05
nucleoside-diphosphatase activity	GO:0017110	7.17
hydrolase activity, acting on acid anhydrides	GO:0016817	3.03
ion binding	GO:0043167	1.36
pyrophosphatase activity	GO:0016462	3.04
cation binding	GO:0043169	1.4
binding	GO:0005488	0.18
nucleoside-triphosphate diphosphatase activity	GO:0047429	7.66
metal ion binding	GO:0046872	1.41
8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity	GO:0035539	9.05