| Disease ID | Disease name | Source of annotation with OGG1 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 144700 | RENAL CELL CARCINOMA, NONPAPILLARY | OMIM | link to OMIM | 7 | VHL, DIRC2, RNF139, HNF1A, OGG1, HNF1B, FLCN |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Base excision repair | hsa03410 | 7.6 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 9.81 |
| Recognition and association of DNA glycosylase with site containing an affected purine | R-HSA-110330 | 11.4 |
| Cleavage of the damaged purine | R-HSA-110331 | 11.4 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 9.98 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 9.98 |
| Depurination | R-HSA-73927 | 11.4 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 7.85 |
| DNA Repair | R-HSA-73894 | 5.8 |
| APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway | R-HSA-5649702 | 10.18 |
| Base Excision Repair | R-HSA-73884 | 7.85 |
| Depyrimidination | R-HSA-73928 | 9.98 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 9.66 |
| GO term | GO ID | GO IC |
|---|---|---|
| hydrolase activity, hydrolyzing N-glycosyl compounds | GO:0016799 | 6.6 |
| hydrolase activity, acting on glycosyl bonds | GO:0016798 | 4.91 |
| binding | GO:0005488 | 0.18 |
| nucleic acid binding | GO:0003676 | 1.44 |
| DNA binding | GO:0003677 | 1.92 |
| heterocyclic compound binding | GO:1901363 | 1.06 |
| oxidized purine DNA binding | GO:0032357 | 8.13 |
| oxidized DNA binding | GO:0032356 | 8.13 |
| lyase activity | GO:0016829 | 4.53 |
| oxidized base lesion DNA N-glycosylase activity | GO:0000702 | 8.64 |
| endodeoxyribonuclease activity | GO:0004520 | 5.81 |
| hydrolase activity | GO:0016787 | 1.9 |
| tubulin binding | GO:0015631 | 4.1 |
| microtubule binding | GO:0008017 | 4.42 |
| DNA N-glycosylase activity | GO:0019104 | 7.03 |
| hydrolase activity, acting on ester bonds | GO:0016788 | 3.1 |
| DNA-(apurinic or apyrimidinic site) lyase activity | GO:0003906 | 7.1 |
| catalytic activity | GO:0003824 | 1.05 |
| 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity | GO:0034039 | 9.74 |
| cytoskeletal protein binding | GO:0008092 | 3.02 |
| nuclease activity | GO:0004518 | 4.33 |
| carbon-oxygen lyase activity | GO:0016835 | 5.46 |
| oxidized purine nucleobase lesion DNA N-glycosylase activity | GO:0008534 | 9.05 |
| deoxyribonuclease activity | GO:0004536 | 5.48 |
| protein binding | GO:0005515 | 0.46 |
| endonuclease activity | GO:0004519 | 4.78 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| damaged DNA binding | GO:0003684 | 5.58 |