Gene table of OPRM1 : opioid receptor mu 1

Gene-disease associations table

Disease IDDisease nameSource of annotation with OPRM1OMIM linkNumber of associated genesgenes
610064OPIOID DEPENDENCE, SUSCEPTIBILITY TO, 1ClinVar link to OMIM 1OPRM1

Download the gene annotation in CSV format

Annotation of the gene OPRM1

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Morphine addictionhsa050326.15
Neuroactive ligand-receptor interactionhsa040804.58
Estrogen signaling pathwayhsa049156.11
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Signaling by GPCRR-HSA-3727902.68
G alpha (i) signalling eventsR-HSA-4185945.1
Opioid SignallingR-HSA-1118856.64
G-protein activationR-HSA-2020408.18
Peptide ligand-binding receptorsR-HSA-3752765.41
GPCR downstream signalingR-HSA-3883963.07
GPCR ligand bindingR-HSA-5007924.19
Class A/1 (Rhodopsin-like receptors)R-HSA-3730764.69
Signal TransductionR-HSA-1625821.78
Associated GO terms for Molecular function
GO termGO IDGO IC
protein C-terminus bindingGO:00080224.5
cation channel activityGO:00052614.04
morphine receptor activityGO:00380479.74
calcium channel activityGO:00052625.03
neuropeptide receptor activityGO:00081885.95
molecular transducer activityGO:00600892.32
bindingGO:00054880.18
signal transducer activityGO:00048712.28
beta-endorphin receptor activityGO:00049799.74
melanocortin receptor activityGO:00049777.95
G-protein coupled peptide receptor activityGO:00085284.86
G-protein coupled receptor activityGO:00049302.95
peptide bindingGO:00422774.22
neuropeptide bindingGO:00429236.65
transmembrane transporter activityGO:00228572.82
divalent inorganic cation transmembrane transporter activityGO:00725094.62
G-protein alpha-subunit bindingGO:00019656.6
voltage-gated cation channel activityGO:00228434.83
transporter activityGO:00052152.57
passive transmembrane transporter activityGO:00228033.6
metal ion transmembrane transporter activityGO:00468733.71
G-protein beta-subunit bindingGO:00316817.54
filamin bindingGO:00310057.17
opioid receptor activityGO:00049857.66
calcium ion transmembrane transporter activityGO:00150854.89
amide bindingGO:00332184.14
ion channel activityGO:00052163.71
cation transmembrane transporter activityGO:00083243.32
peptide receptor activityGO:00016534.84
protein domain specific bindingGO:00199043.32
voltage-gated calcium channel activityGO:00052456.0
voltage-gated ion channel activityGO:00052444.49
substrate-specific transmembrane transporter activityGO:00228912.9
inorganic cation transmembrane transporter activityGO:00228903.49
substrate-specific transporter activityGO:00228922.72
cytoskeletal protein bindingGO:00080923.02
ion transmembrane transporter activityGO:00150753.04
voltage-gated channel activityGO:00228324.49
transmembrane signaling receptor activityGO:00048882.57
channel activityGO:00152673.6
gated channel activityGO:00228363.96
protein bindingGO:00055150.46
signaling receptor activityGO:00380232.49
substrate-specific channel activityGO:00228383.67
transmembrane receptor activityGO:00996002.53
receptor activityGO:00048722.32