Gene table of PAPSS2 : 3'-phosphoadenosine 5'-phosphosulfate synthase 2

Gene-disease associations table

Disease ID	Disease name	Source of annotation with PAPSS2	OMIM link	Number of associated genes	genes
612847	BRACHYOLMIA TYPE 4 WITH MILD EPIPHYSEAL AND METAPHYSEAL CHANGES	ClinVar, OMIM, HUMSAVAR	link to OMIM	1	PAPSS2

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Cytosolic sulfonation of small molecules	R-HSA-156584	8.89
Metabolism of carbohydrates	R-HSA-71387	4.93
Biological oxidations	R-HSA-211859	5.55
Defective PAPSS2 causes SEMD-PA	R-HSA-3560796	12.98
Diseases associated with glycosaminoglycan metabolism	R-HSA-3560782	7.77
Phase II conjugation	R-HSA-156580	6.52
Metabolism	R-HSA-1430728	2.34
Diseases of glycosylation	R-HSA-3781865	6.89
Glycosaminoglycan metabolism	R-HSA-1630316	6.04
Transport and synthesis of PAPS	R-HSA-174362	10.4
Disease	R-HSA-1643685	3.33

Associated GO terms for Molecular function

GO term	GO ID	GO IC
purine ribonucleoside triphosphate binding	GO:0035639	2.22
binding	GO:0005488	0.18
heterocyclic compound binding	GO:1901363	1.06
nucleoside phosphate binding	GO:1901265	1.96
nucleoside binding	GO:0001882	2.21
nucleotide binding	GO:0000166	1.96
transferase activity	GO:0016740	1.95
purine nucleoside binding	GO:0001883	2.22
ribonucleoside binding	GO:0032549	2.22
purine nucleotide binding	GO:0017076	2.19
ATP binding	GO:0005524	2.43
sulfate adenylyltransferase activity	GO:0004779	9.05
kinase activity	GO:0016301	2.93
adenylylsulfate kinase activity	GO:0004020	9.05
small molecule binding	GO:0036094	1.89
catalytic activity	GO:0003824	1.05
sulfate adenylyltransferase (ATP) activity	GO:0004781	9.05
nucleotidyltransferase activity	GO:0016779	4.81
adenyl nucleotide binding	GO:0030554	2.4
phosphotransferase activity, alcohol group as acceptor	GO:0016773	3.08
organic cyclic compound binding	GO:0097159	1.05
adenylyltransferase activity	GO:0070566	6.56
carbohydrate derivative binding	GO:0097367	2.03
adenyl ribonucleotide binding	GO:0032559	2.41
transferase activity, transferring phosphorus-containing groups	GO:0016772	2.77
purine ribonucleotide binding	GO:0032555	2.2
purine ribonucleoside binding	GO:0032550	2.22
ribonucleotide binding	GO:0032553	2.19