Gene table of PDP1 : pyruvate dehyrogenase phosphatase catalytic subunit 1

Gene-disease associations table

Disease IDDisease nameSource of annotation with PDP1OMIM linkNumber of associated genesgenes
PS312170PYRUVATE DEHYDROGENASE COMPLEX DEFICIENCYClinVar, OMIM link to OMIM 6PDHX, PDHA1, PDHB, PDP1, LIAS, DLAT

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Annotation of the gene PDP1

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Regulation of pyruvate dehydrogenase (PDH) complexR-HSA-2041749.18
The citric acid (TCA) cycle and respiratory electron transportR-HSA-14285175.71
Pyruvate metabolismR-HSA-702688.52
Pyruvate metabolism and Citric Acid (TCA) cycleR-HSA-714067.56
MetabolismR-HSA-14307282.34
Associated GO terms for Molecular function
GO termGO IDGO IC
phosphoprotein phosphatase activityGO:00047214.55
magnesium-dependent protein serine/threonine phosphatase activityGO:00047249.05
phosphatase activityGO:00167914.11
hydrolase activityGO:00167871.9
[pyruvate dehydrogenase (lipoamide)] phosphatase activityGO:00047418.64
magnesium ion bindingGO:00002874.41
protein serine/threonine phosphatase activityGO:00047225.58
hydrolase activity, acting on ester bondsGO:00167883.1
ion bindingGO:00431671.36
phosphoric ester hydrolase activityGO:00425783.82
catalytic activityGO:00038241.05
cation bindingGO:00431691.4
macromolecular complex bindingGO:00448772.61
bindingGO:00054880.18
protein bindingGO:00055150.46
protein complex bindingGO:00324033.09
metal ion bindingGO:00468721.41
calcium ion bindingGO:00055093.17