Gene table of PDYN : prodynorphin

Gene-disease associations table

Disease IDDisease nameSource of annotation with PDYNOMIM linkNumber of associated genesgenes
PS164400SPINOCEREBELLAR ATAXIAClinVar, OMIM, HUMSAVAR link to OMIM 31ATXN10, ATXN2, SCYL1, PDYN, ELOVL5, PRKCG, TRPC3, ATXN8OS, NOP56, ATXN8, TBP, PPP2R2B, ELOVL4, PLEKHG4, ATXN7, AFG3L2, BEAN1, CACNA1A, ATXN1, TTBK2, KCND3, CACNA1G, TMEM240, ATXN3, KCNC3, SPTBN2, TGM6, CCDC88C, FGF14, ITPR1, EEF2

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Annotation of the gene PDYN

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Cocaine addictionhsa050307.07
Amphetamine addictionhsa050316.62
Alcoholismhsa050345.59
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Signaling by GPCRR-HSA-3727902.68
G alpha (i) signalling eventsR-HSA-4185945.1
Opioid SignallingR-HSA-1118856.64
G-protein activationR-HSA-2020408.18
Peptide ligand-binding receptorsR-HSA-3752765.41
GPCR downstream signalingR-HSA-3883963.07
GPCR ligand bindingR-HSA-5007924.19
Class A/1 (Rhodopsin-like receptors)R-HSA-3730764.69
Signal TransductionR-HSA-1625821.78
Associated GO terms for Molecular function
GO termGO IDGO IC
hormone activityGO:00051794.95
neuropeptide hormone activityGO:00051846.34
opioid receptor bindingGO:00316287.54
opioid peptide activityGO:00015158.35
bindingGO:00054880.18
protein bindingGO:00055150.46
G-protein coupled receptor bindingGO:00016644.18
receptor bindingGO:00051022.43