Gene table of PINK1 : PTEN induced putative kinase 1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with PINK1	OMIM link	Number of associated genes	genes
PS168600	PARKINSON DISEASE	ClinVar, OMIM, HUMSAVAR	link to OMIM	30	ATP13A2, FGF20, VPS13C, DNAJC13, ATXN2, PINK1, CHCHD2, ADH1C, UCHL1, GIGYF2, SYNJ1, PODXL, HTRA2, LRRK2, TBP, PARK2, ATXN8OS, SNCAIP, GBA, SNCA, NR4A2, PLA2G6, GLUD2, PARK7, ATXN3, MAPT, DNAJC6, EIF4G1, FBXO7, VPS35

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Annotation of the gene PINK1

Associated genes in ENSEMBL

ENSG00000158828

Associated proteins - SwissProt Accession ID

Q9BXM7

Associated PDB IDs

Cytogenetic Band

1p36.12

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Parkinson's disease	hsa05012	5.59

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
ubiquitin-like protein ligase binding	GO:0044389	4.15
purine ribonucleoside triphosphate binding	GO:0035639	2.22
enzyme binding	GO:0019899	2.27
binding	GO:0005488	0.18
nucleotide binding	GO:0000166	1.96
heterocyclic compound binding	GO:1901363	1.06
nucleoside phosphate binding	GO:1901265	1.96
nucleoside binding	GO:0001882	2.21
cation binding	GO:0043169	1.4
molecular function regulator	GO:0098772	2.51
magnesium ion binding	GO:0000287	4.41
ribonucleoside binding	GO:0032549	2.22
ion binding	GO:0043167	1.36
purine ribonucleotide binding	GO:0032555	2.2
protein serine/threonine kinase activity	GO:0004674	3.64
transferase activity	GO:0016740	1.95
purine nucleoside binding	GO:0001883	2.22
protease binding	GO:0002020	5.08
protein kinase activity	GO:0004672	3.27
purine nucleotide binding	GO:0017076	2.19
metal ion binding	GO:0046872	1.41
ATP binding	GO:0005524	2.43
kinase activity	GO:0016301	2.93
enzyme regulator activity	GO:0030234	2.85
peptidase regulator activity	GO:0061134	4.37
protein kinase binding	GO:0019901	3.44
kinase binding	GO:0019900	3.32
protein domain specific binding	GO:0019904	3.32
calcium-dependent protein kinase activity	GO:0010857	7.25
protein kinase B binding	GO:0043422	7.44
C3HC4-type RING finger domain binding	GO:0055131	7.95
small molecule binding	GO:0036094	1.89
ubiquitin protein ligase binding	GO:0031625	4.17
adenyl nucleotide binding	GO:0030554	2.4
carbohydrate derivative binding	GO:0097367	2.03
organic cyclic compound binding	GO:0097159	1.05
catalytic activity	GO:0003824	1.05
phosphotransferase activity, alcohol group as acceptor	GO:0016773	3.08
adenyl ribonucleotide binding	GO:0032559	2.41
protein binding	GO:0005515	0.46
transferase activity, transferring phosphorus-containing groups	GO:0016772	2.77
peptidase activator activity	GO:0016504	6.13
purine ribonucleoside binding	GO:0032550	2.22
ribonucleotide binding	GO:0032553	2.19
enzyme activator activity	GO:0008047	3.56