| Disease ID | Disease name | Source of annotation with PLA2G7 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 147050 | IGE RESPONSIVENESS, ATOPIC | OMIM | link to OMIM | 8 | HAVCR1, PLA2G7, MS4A2, PHF11, SELP, IL4R, SPINK5, IL21R |
| 614278 | PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE DEFICIENCY | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | PLA2G7 |
| 600807 | ASTHMA, SUSCEPTIBILITY TO | OMIM | link to OMIM | 13 | HLA-G, SCGB1A1, PLA2G7, PHF11, MUC7, TNF, HNMT, IL13, SPINK5, SCGB3A2, CCL11, ALOX5, ADRB2 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Metabolic pathways | hsa01100 | 2.49 |
| Ether lipid metabolism | hsa00565 | 7.28 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Metabolism of proteins | R-HSA-392499 | 3.41 |
| Peptide hormone metabolism | R-HSA-2980736 | 6.61 |
| Synthesis, secretion, and deacylation of Ghrelin | R-HSA-422085 | 8.89 |
| GO term | GO ID | GO IC |
|---|---|---|
| hydrolase activity | GO:0016787 | 1.9 |
| carboxylic ester hydrolase activity | GO:0052689 | 4.81 |
| calcium-independent phospholipase A2 activity | GO:0047499 | 8.13 |
| phospholipid binding | GO:0005543 | 3.91 |
| lipid binding | GO:0008289 | 3.26 |
| hydrolase activity, acting on ester bonds | GO:0016788 | 3.1 |
| catalytic activity | GO:0003824 | 1.05 |
| 1-alkyl-2-acetylglycerophosphocholine esterase activity | GO:0003847 | 8.13 |
| binding | GO:0005488 | 0.18 |
| phospholipase A2 activity | GO:0004623 | 6.24 |
| phospholipase activity | GO:0004620 | 5.16 |
| lipase activity | GO:0016298 | 4.96 |