Gene table of PLEKHG2 : pleckstrin homology and RhoGEF domain containing G2

Gene-disease associations table

Disease IDDisease nameSource of annotation with PLEKHG2OMIM linkNumber of associated genesgenes
616763LEUKODYSTROPHY AND ACQUIRED MICROCEPHALY WITH OR WITHOUT DYSTONIAOMIM link to OMIM 1PLEKHG2

Download the gene annotation in CSV format

Annotation of the gene PLEKHG2

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
p75 NTR receptor-mediated signallingR-HSA-1937046.59
Signalling by NGFR-HSA-1665204.23
G alpha (12/13) signalling eventsR-HSA-4164826.75
GPCR downstream signalingR-HSA-3883963.07
Signaling by Rho GTPasesR-HSA-1943154.43
Rho GTPase cycleR-HSA-1948406.04
Cell death signalling via NRAGE, NRIF and NADER-HSA-2049987.05
Signaling by GPCRR-HSA-3727902.68
Signal TransductionR-HSA-1625821.78
NRAGE signals death through JNKR-HSA-1936487.49
Associated GO terms for Molecular function
GO termGO IDGO IC
Rho guanyl-nucleotide exchange factor activityGO:00050895.37
Ras guanyl-nucleotide exchange factor activityGO:00050884.31
guanyl-nucleotide exchange factor activityGO:00050854.02
bindingGO:00054880.18
protein bindingGO:00055150.46
molecular function regulatorGO:00987722.51