Gene table of POLG2 : DNA polymerase gamma 2, accessory subunit

Gene-disease associations table

Disease ID	Disease name	Source of annotation with POLG2	OMIM link	Number of associated genes	genes
PS157640	PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA WITH MTDNA DELETIONS	ClinVar, OMIM, HUMSAVAR	link to OMIM	7	SLC25A4, DNA2, C10orf2, RRM2B, RNASEH1, POLG, POLG2

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Metabolic pathways	hsa01100	2.49

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Mitochondrial biogenesis	R-HSA-1592230	7.34
Organelle biogenesis and maintenance	R-HSA-1852241	4.63
Transcriptional activation of mitochondrial biogenesis	R-HSA-2151201	7.62

Associated GO terms for Molecular function

GO term	GO ID	GO IC
nucleotidyltransferase activity	GO:0016779	4.81
aminoacyl-tRNA ligase activity	GO:0004812	5.93
glycine-tRNA ligase activity	GO:0004820	9.05
nucleic acid binding	GO:0003676	1.44
organic cyclic compound binding	GO:0097159	1.05
DNA binding	GO:0003677	1.92
DNA polymerase activity	GO:0034061	5.93
ligase activity, forming carbon-oxygen bonds	GO:0016875	5.93
DNA-directed DNA polymerase activity	GO:0003887	6.41
catalytic activity	GO:0003824	1.05
transferase activity	GO:0016740	1.95
binding	GO:0005488	0.18
protein binding	GO:0005515	0.46
transferase activity, transferring phosphorus-containing groups	GO:0016772	2.77
ligase activity, forming aminoacyl-tRNA and related compounds	GO:0016876	5.93
ligase activity	GO:0016874	3.72
heterocyclic compound binding	GO:1901363	1.06
identical protein binding	GO:0042802	2.63