Gene table of PON1 : paraoxonase 1

Gene-disease associations table

Disease IDDisease nameSource of annotation with PON1OMIM linkNumber of associated genesgenes
PS603933MICROVASCULAR COMPLICATIONS OF DIABETESClinVar, OMIM link to OMIM 7EPO, ACE, PON1, IL1RN, SOD2, HFE, VEGFA

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Annotation of the gene PON1

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Metabolic pathwayshsa011002.49
Associated REACTOME pathways
Associated GO terms for Molecular function
GO termGO IDGO IC
hydrolase activityGO:00167871.9
metal ion bindingGO:00468721.41
phosphatase activityGO:00167914.11
lactonohydrolase activityGO:00465738.64
carboxylic ester hydrolase activityGO:00526894.81
catalytic activityGO:00038241.05
phospholipid bindingGO:00055433.91
lipid bindingGO:00082893.26
hydrolase activity, acting on ester bondsGO:00167883.1
ion bindingGO:00431671.36
phosphoric ester hydrolase activityGO:00425783.82
protein homodimerization activityGO:00428033.16
cation bindingGO:00431691.4
bindingGO:00054880.18
protein bindingGO:00055150.46
acyl-L-homoserine-lactone lactonohydrolase activityGO:01020078.64
protein dimerization activityGO:00469832.72
aryldialkylphosphatase activityGO:00040639.05
arylesterase activityGO:00040647.95
identical protein bindingGO:00428022.63
calcium ion bindingGO:00055093.17