Gene table of PPARGC1B : PPARG coactivator 1 beta

Gene-disease associations table

Disease ID	Disease name	Source of annotation with PPARGC1B	OMIM link	Number of associated genes	genes
601665	OBESITY	OMIM	link to OMIM	15	PPARGC1B, AGRP, PPARG, MC4R, ADRB3, CARTPT, UCP3, SIM1, POMC, ENPP1, ADRB2, SDC3, NR0B2, UCP1, GHRL

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
PPARA activates gene expression	R-HSA-1989781	6.18
Organelle biogenesis and maintenance	R-HSA-1852241	4.63
Transcriptional activation of mitochondrial biogenesis	R-HSA-2151201	7.62
Mitochondrial biogenesis	R-HSA-1592230	7.34
Metabolism	R-HSA-1430728	2.34
Fatty acid, triacylglycerol, and ketone body metabolism	R-HSA-535734	5.44
Metabolism of lipids and lipoproteins	R-HSA-556833	3.79
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)	R-HSA-400206	6.14

Associated GO terms for Molecular function

GO term	GO ID	GO IC
AF-2 domain binding	GO:0050682	8.64
transcription factor activity, RNA polymerase II transcription factor binding	GO:0001076	4.84
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
molecular function regulator	GO:0098772	2.51
heterocyclic compound binding	GO:1901363	1.06
nucleoside phosphate binding	GO:1901265	1.96
receptor regulator activity	GO:0030545	5.91
receptor activator activity	GO:0030546	6.27
transcription coactivator activity	GO:0003713	4.04
transcription cofactor activity	GO:0003712	3.44
nucleotide binding	GO:0000166	1.96
transcription factor activity, transcription factor binding	GO:0000989	3.36
transcription factor activity, protein binding	GO:0000988	3.35
steroid hormone receptor binding	GO:0035258	5.32
estrogen receptor binding	GO:0030331	6.05
transcription factor binding	GO:0008134	3.46
nuclear hormone receptor binding	GO:0035257	4.7
ligand-dependent nuclear receptor transcription coactivator activity	GO:0030374	5.77
RNA polymerase II transcription cofactor activity	GO:0001104	5.22
protein domain specific binding	GO:0019904	3.32
hormone receptor binding	GO:0051427	4.57
small molecule binding	GO:0036094	1.89
organic cyclic compound binding	GO:0097159	1.05
RNA binding	GO:0003723	2.36
protein binding	GO:0005515	0.46
receptor binding	GO:0005102	2.43