Gene table of PPOX : protoporphyrinogen oxidase

Gene-disease associations table

Disease IDDisease nameSource of annotation with PPOXOMIM linkNumber of associated genesgenes
176200PORPHYRIA VARIEGATAClinVar, OMIM, HUMSAVAR link to OMIM 2HFE, PPOX

Download the gene annotation in CSV format

Annotation of the gene PPOX

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Porphyrin and chlorophyll metabolismhsa008607.41
Metabolic pathwayshsa011002.49
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Heme biosynthesisR-HSA-1894519.52
MetabolismR-HSA-14307282.34
Metabolism of porphyrinsR-HSA-1894458.89
Associated GO terms for Molecular function
GO termGO IDGO IC
coenzyme bindingGO:00506624.53
protoporphyrinogen oxidase activityGO:00708189.74
flavin adenine dinucleotide bindingGO:00506605.41
oxygen-dependent protoporphyrinogen oxidase activityGO:00047299.74
organic cyclic compound bindingGO:00971591.05
oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptorGO:00166347.54
nucleotide bindingGO:00001661.96
small molecule bindingGO:00360941.89
catalytic activityGO:00038241.05
oxidoreductase activity, acting on the CH-CH group of donorsGO:00166275.66
cofactor bindingGO:00480374.16
bindingGO:00054880.18
heterocyclic compound bindingGO:19013631.06
nucleoside phosphate bindingGO:19012651.96
oxidoreductase activityGO:00164913.12