Gene table of PRKCH : protein kinase C eta

Gene-disease associations table

Disease ID	Disease name	Source of annotation with PRKCH	OMIM link	Number of associated genes	genes
601367	STROKE, ISCHEMIC	OMIM	link to OMIM	5	PRKCH, NOS3, ALOX5AP, F5, F2

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Tight junction	hsa04530	5.53
Inflammatory mediator regulation of TRP channels	hsa04750	6.07
Vascular smooth muscle contraction	hsa04270	5.74

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Signaling by GPCR	R-HSA-372790	2.68
GPCR downstream signaling	R-HSA-388396	3.07
G alpha (z) signalling events	R-HSA-418597	7.46
Gastrin-CREB signalling pathway via PKC and MAPK	R-HSA-881907	4.26
G alpha (q) signalling events	R-HSA-416476	5.42
Effects of PIP2 hydrolysis	R-HSA-114508	8.34
Hemostasis	R-HSA-109582	3.98
Signal Transduction	R-HSA-162582	1.78
Platelet activation, signaling and aggregation	R-HSA-76002	5.15

Associated GO terms for Molecular function

GO term	GO ID	GO IC
Ral GTPase binding	GO:0017160	7.17
purine ribonucleoside triphosphate binding	GO:0035639	2.22
enzyme binding	GO:0019899	2.27
small GTPase binding	GO:0031267	4.13
calcium-independent protein kinase C activity	GO:0004699	8.64
binding	GO:0005488	0.18
nucleotide binding	GO:0000166	1.96
protein kinase C activity	GO:0004697	6.97
heterocyclic compound binding	GO:1901363	1.06
nucleoside phosphate binding	GO:1901265	1.96
nucleoside binding	GO:0001882	2.21
cation binding	GO:0043169	1.4
ribonucleoside binding	GO:0032549	2.22
ion binding	GO:0043167	1.36
protein serine/threonine kinase activity	GO:0004674	3.64
transferase activity	GO:0016740	1.95
purine nucleoside binding	GO:0001883	2.22
protein kinase activity	GO:0004672	3.27
purine nucleotide binding	GO:0017076	2.19
metal ion binding	GO:0046872	1.41
ATP binding	GO:0005524	2.43
kinase activity	GO:0016301	2.93
Ras GTPase binding	GO:0017016	4.2
small molecule binding	GO:0036094	1.89
catalytic activity	GO:0003824	1.05
adenyl nucleotide binding	GO:0030554	2.4
phosphotransferase activity, alcohol group as acceptor	GO:0016773	3.08
organic cyclic compound binding	GO:0097159	1.05
GTPase binding	GO:0051020	4.05
carbohydrate derivative binding	GO:0097367	2.03
adenyl ribonucleotide binding	GO:0032559	2.41
protein binding	GO:0005515	0.46
transferase activity, transferring phosphorus-containing groups	GO:0016772	2.77
purine ribonucleotide binding	GO:0032555	2.2
purine ribonucleoside binding	GO:0032550	2.22
ribonucleotide binding	GO:0032553	2.19