Gene table of PROP1 : PROP paired-like homeobox 1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with PROP1	OMIM link	Number of associated genes	genes
PS613038	PITUITARY HORMONE DEFICIENCY, COMBINED	ClinVar, OMIM, HUMSAVAR	link to OMIM	6	OTX2, PROP1, HESX1, LHX3, POU1F1, LHX4

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Annotation of the gene PROP1

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

O75360

Associated PDB IDs

Cytogenetic Band

5q35.3

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
protein C-terminus binding	GO:0008022	4.5
RNA polymerase II regulatory region DNA binding	GO:0001012	3.36
enhancer sequence-specific DNA binding	GO:0001158	5.36
macromolecular complex binding	GO:0044877	2.61
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
DNA binding	GO:0003677	1.92
heterocyclic compound binding	GO:1901363	1.06
sequence-specific DNA binding	GO:0043565	2.79
sequence-specific double-stranded DNA binding	GO:1990837	3.2
double-stranded DNA binding	GO:0003690	3.09
RNA polymerase II transcription factor activity, sequence-specific DNA binding	GO:0000981	3.29
RNA polymerase II distal enhancer sequence-specific DNA binding	GO:0000980	5.58
regulatory region nucleic acid binding	GO:0001067	3.03
beta-catenin binding	GO:0008013	5.3
enhancer binding	GO:0035326	5.21
transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding	GO:0001206	7.54
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding	GO:0001205	6.48
transcription regulatory region DNA binding	GO:0044212	3.03
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding	GO:0001227	4.61
transcription factor activity, sequence-specific DNA binding	GO:0003700	2.65
organic cyclic compound binding	GO:0097159	1.05
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding	GO:0003705	5.23
transcription regulatory region sequence-specific DNA binding	GO:0000976	3.24
RNA polymerase II regulatory region sequence-specific DNA binding	GO:0000977	3.37
protein binding	GO:0005515	0.46
regulatory region DNA binding	GO:0000975	3.03
chromatin binding	GO:0003682	3.64
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	GO:0001228	3.98
nucleic acid binding transcription factor activity	GO:0001071	2.65