| Disease ID | Disease name | Source of annotation with PRSS2 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 167800 | PANCREATITIS, HEREDITARY | OMIM | link to OMIM | 5 | PRSS2, SPINK1, CTRC, PRSS1, CFTR |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Influenza A | hsa05164 | 5.21 |
| Protein digestion and absorption | hsa04974 | 6.2 |
| Pancreatic secretion | hsa04972 | 6.07 |
| Neuroactive ligand-receptor interaction | hsa04080 | 4.58 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Defensins | R-HSA-1461973 | 7.49 |
| Innate Immune System | R-HSA-168249 | 3.17 |
| Immune System | R-HSA-168256 | 2.37 |
| Degradation of the extracellular matrix | R-HSA-1474228 | 6.11 |
| Collagen degradation | R-HSA-1442490 | 7.03 |
| Activation of Matrix Metalloproteinases | R-HSA-1592389 | 8.03 |
| Extracellular matrix organization | R-HSA-1474244 | 4.91 |
| Alpha-defensins | R-HSA-1462054 | 9.81 |
| GO term | GO ID | GO IC |
|---|---|---|
| hydrolase activity | GO:0016787 | 1.9 |
| endopeptidase activity | GO:0004175 | 3.63 |
| serine-type endopeptidase activity | GO:0004252 | 4.4 |
| serine hydrolase activity | GO:0017171 | 4.26 |
| metal ion binding | GO:0046872 | 1.41 |
| cation binding | GO:0043169 | 1.4 |
| ion binding | GO:0043167 | 1.36 |
| catalytic activity | GO:0003824 | 1.05 |
| peptidase activity, acting on L-amino acid peptides | GO:0070011 | 3.26 |
| calcium ion binding | GO:0005509 | 3.17 |
| protein binding | GO:0005515 | 0.46 |
| peptidase activity | GO:0008233 | 3.23 |
| serine-type peptidase activity | GO:0008236 | 4.27 |
| binding | GO:0005488 | 0.18 |