Gene table of PTPRO : protein tyrosine phosphatase, receptor type O

Gene-disease associations table

Disease ID	Disease name	Source of annotation with PTPRO	OMIM link	Number of associated genes	genes
PS256300	NEPHROTIC SYNDROME	ClinVar, OMIM	link to OMIM	14	LAMB2, NUP93, NUP205, NPHS1, OPA1, NPHS2, ADCK4, NUP107, WT1, ARHGDIA, PTPRO, PLCE1, EMP2, DGKE

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
hydrolase activity	GO:0016787	1.9
signaling receptor activity	GO:0038023	2.49
protein binding	GO:0005515	0.46
hydrolase activity, acting on ester bonds	GO:0016788	3.1
protein tyrosine phosphatase activity	GO:0004725	5.09
phosphoprotein phosphatase activity	GO:0004721	4.55
transmembrane receptor protein tyrosine phosphatase activity	GO:0005001	6.91
catalytic activity	GO:0003824	1.05
transmembrane signaling receptor activity	GO:0004888	2.57
identical protein binding	GO:0042802	2.63
phosphoric ester hydrolase activity	GO:0042578	3.82
receptor activity	GO:0004872	2.32
signal transducer activity	GO:0004871	2.28
Wnt-protein binding	GO:0017147	6.3
phosphatase activity	GO:0016791	4.11
transmembrane receptor protein phosphatase activity	GO:0019198	6.91
protein homodimerization activity	GO:0042803	3.16
molecular transducer activity	GO:0060089	2.32
protein dimerization activity	GO:0046983	2.72
transmembrane receptor activity	GO:0099600	2.53
binding	GO:0005488	0.18