Gene table of PTPRO : protein tyrosine phosphatase, receptor type O

Gene-disease associations table

Disease IDDisease nameSource of annotation with PTPROOMIM linkNumber of associated genesgenes
PS256300NEPHROTIC SYNDROMEClinVar, OMIM link to OMIM 14LAMB2, NUP93, NUP205, NPHS1, OPA1, NPHS2, ADCK4, NUP107, WT1, ARHGDIA, PTPRO, PLCE1, EMP2, DGKE

Download the gene annotation in CSV format

Annotation of the gene PTPRO

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
Associated REACTOME pathways
Associated GO terms for Molecular function
GO termGO IDGO IC
hydrolase activityGO:00167871.9
signaling receptor activityGO:00380232.49
protein bindingGO:00055150.46
hydrolase activity, acting on ester bondsGO:00167883.1
protein tyrosine phosphatase activityGO:00047255.09
phosphoprotein phosphatase activityGO:00047214.55
transmembrane receptor protein tyrosine phosphatase activityGO:00050016.91
catalytic activityGO:00038241.05
transmembrane signaling receptor activityGO:00048882.57
identical protein bindingGO:00428022.63
phosphoric ester hydrolase activityGO:00425783.82
receptor activityGO:00048722.32
signal transducer activityGO:00048712.28
Wnt-protein bindingGO:00171476.3
phosphatase activityGO:00167914.11
transmembrane receptor protein phosphatase activityGO:00191986.91
protein homodimerization activityGO:00428033.16
molecular transducer activityGO:00600892.32
protein dimerization activityGO:00469832.72
transmembrane receptor activityGO:00996002.53
bindingGO:00054880.18