Gene table of RBBP8 : RB binding protein 8, endonuclease

Gene-disease associations table

Disease IDDisease nameSource of annotation with RBBP8OMIM linkNumber of associated genesgenes
251255JAWAD SYNDROMEOMIM link to OMIM 1RBBP8
260350PANCREATIC CANCERClinVar, OMIM link to OMIM 6STK11, KRAS, ACVR1B, RBBP8, SMAD4, TP53
PS210600SECKEL SYNDROMEClinVar, OMIM, HUMSAVAR link to OMIM 8NIN, CEP63, DNA2, TRAIP, RBBP8, CEP152, ATR, CENPJ

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Annotation of the gene RBBP8

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Cell CycleR-HSA-16401703.89
MeiosisR-HSA-15006206.59
Meiotic recombinationR-HSA-9124467.25
Associated GO terms for Molecular function
GO termGO IDGO IC
endodeoxyribonuclease activityGO:00045205.81
transcription factor activity, RNA polymerase II transcription factor bindingGO:00010764.84
bindingGO:00054880.18
nucleic acid bindingGO:00036761.44
DNA bindingGO:00036771.92
heterocyclic compound bindingGO:19013631.06
repressing transcription factor bindingGO:00704915.71
transcriptional repressor activity, RNA polymerase II transcription factor bindingGO:00011915.28
transcription corepressor activityGO:00037144.33
transcription cofactor activityGO:00037123.44
transcription factor activity, transcription factor bindingGO:00009893.36
transcription factor activity, protein bindingGO:00009883.35
hydrolase activityGO:00167871.9
transcription factor bindingGO:00081343.46
hydrolase activity, acting on ester bondsGO:00167883.1
RNA polymerase II transcription cofactor activityGO:00011045.22
catalytic activityGO:00038241.05
RNA polymerase II transcription corepressor activityGO:00011066.48
RNA polymerase II repressing transcription factor bindingGO:00011036.44
RNA polymerase II transcription factor bindingGO:00010855.08
single-stranded DNA endodeoxyribonuclease activityGO:00000147.79
nuclease activityGO:00045184.33
endonuclease activityGO:00045194.78
deoxyribonuclease activityGO:00045365.48
protein bindingGO:00055150.46
organic cyclic compound bindingGO:00971591.05
damaged DNA bindingGO:00036845.58