Disease ID | Disease name | Source of annotation with RNASEH2B | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
PS225750 | AICARDI-GOUTIERES SYNDROME | ClinVar, OMIM, HUMSAVAR | link to OMIM | 7 | IFIH1, RNASEH2B, RNASEH2C, RNASEH2A, ADAR, TREX1, SAMHD1 |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
DNA replication | hsa03030 | 7.48 |
GO term | GO ID | GO IC |
---|---|---|
hydrolase activity | GO:0016787 | 1.9 |
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | GO:0016893 | 5.83 |
nuclease activity | GO:0004518 | 4.33 |
endonuclease activity | GO:0004519 | 4.78 |
ribonuclease activity | GO:0004540 | 5.04 |
endoribonuclease activity | GO:0004521 | 5.58 |
hydrolase activity, acting on ester bonds | GO:0016788 | 3.1 |
catalytic activity | GO:0003824 | 1.05 |
endoribonuclease activity, producing 5'-phosphomonoesters | GO:0016891 | 6.02 |
RNA-DNA hybrid ribonuclease activity | GO:0004523 | 6.74 |