Gene table of RNF168 : ring finger protein 168

Gene-disease associations table

Disease ID	Disease name	Source of annotation with RNF168	OMIM link	Number of associated genes	genes
611943	RIDDLE SYNDROME	ClinVar, OMIM	link to OMIM	1	RNF168

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
G2/M Checkpoints	R-HSA-69481	6.46
G2/M DNA damage checkpoint	R-HSA-69473	7.15
Metabolism of proteins	R-HSA-392499	3.41
Cell Cycle Checkpoints	R-HSA-69620	5.64
SUMOylation	R-HSA-2990846	6.68
SUMOylation of DNA damage response and repair proteins	R-HSA-3108214	6.77
Cell Cycle	R-HSA-1640170	3.89
Post-translational protein modification	R-HSA-597592	4.54
SUMO E3 ligases SUMOylate target proteins	R-HSA-3108232	6.77

Associated GO terms for Molecular function

GO term	GO ID	GO IC
ubiquitin-like protein transferase activity	GO:0019787	3.69
cation binding	GO:0043169	1.4
histone binding	GO:0042393	4.72
transition metal ion binding	GO:0046914	2.48
ubiquitin-protein transferase activity	GO:0004842	3.73
chromatin binding	GO:0003682	3.64
ubiquitin-like protein binding	GO:0032182	4.93
ion binding	GO:0043167	1.36
nucleosome binding	GO:0031491	5.95
catalytic activity	GO:0003824	1.05
transferase activity	GO:0016740	1.95
ubiquitin binding	GO:0043130	5.09
macromolecular complex binding	GO:0044877	2.61
binding	GO:0005488	0.18
protein binding	GO:0005515	0.46
polyubiquitin binding	GO:0031593	5.98
protein complex binding	GO:0032403	3.09
K63-linked polyubiquitin binding	GO:0070530	6.79
metal ion binding	GO:0046872	1.41
ligase activity	GO:0016874	3.72
zinc ion binding	GO:0008270	2.66