Gene table of RNF6 : ring finger protein 6

Gene-disease associations table

Disease ID	Disease name	Source of annotation with RNF6	OMIM link	Number of associated genes	genes
133239	ESOPHAGEAL CANCER	OMIM	link to OMIM	7	TGFBR2, DCC, DLEC1, RNF6, DEC1, WWOX, LZTS1

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Class I MHC mediated antigen processing & presentation	R-HSA-983169	4.65
Antigen processing: Ubiquitination & Proteasome degradation	R-HSA-983168	5.19
Immune System	R-HSA-168256	2.37
Adaptive Immune System	R-HSA-1280218	3.19

Associated GO terms for Molecular function

GO term	GO ID	GO IC
androgen receptor binding	GO:0050681	6.07
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
DNA binding	GO:0003677	1.92
heterocyclic compound binding	GO:1901363	1.06
ubiquitin-like protein transferase activity	GO:0019787	3.69
cation binding	GO:0043169	1.4
transition metal ion binding	GO:0046914	2.48
ubiquitin protein ligase activity	GO:0061630	4.47
ion binding	GO:0043167	1.36
transferase activity	GO:0016740	1.95
metal ion binding	GO:0046872	1.41
steroid hormone receptor binding	GO:0035258	5.32
nuclear hormone receptor binding	GO:0035257	4.7
catalytic activity	GO:0003824	1.05
hormone receptor binding	GO:0051427	4.57
ubiquitin-protein transferase activity	GO:0004842	3.73
ubiquitin-like protein ligase activity	GO:0061659	4.44
organic cyclic compound binding	GO:0097159	1.05
protein binding	GO:0005515	0.46
receptor binding	GO:0005102	2.43
ligase activity	GO:0016874	3.72
zinc ion binding	GO:0008270	2.66