Gene table of RSPO4 : R-spondin 4

Gene-disease associations table

Disease ID	Disease name	Source of annotation with RSPO4	OMIM link	Number of associated genes	genes
PS161050	NAIL DISORDER, NONSYNDROMIC CONGENITAL	ClinVar, OMIM, HUMSAVAR	link to OMIM	4	PLCD1, FZD6, RSPO4, COL7A1

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
TCF dependent signaling in response to WNT	R-HSA-201681	5.36
regulation of FZD by ubiquitination	R-HSA-4641263	8.59
Signaling by Wnt	R-HSA-195721	4.79
Signal Transduction	R-HSA-162582	1.78

Associated GO terms for Molecular function

GO term	GO ID	GO IC
sulfur compound binding	GO:1901681	4.32
carbohydrate derivative binding	GO:0097367	2.03
glycosaminoglycan binding	GO:0005539	4.42
heparin binding	GO:0008201	4.68
binding	GO:0005488	0.18