Disease ID | Disease name | Source of annotation with RTN4R | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
181500 | SCHIZOPHRENIA | OMIM | link to OMIM | 17 | COMT, DISC2, MTHFR, DISC1, CHI3L1, SYN2, MC4R, DAO, AKT1, HTR2A, APOL2, DTNBP1, SETD1A, DRD3, APOL4, RTN4R, DAOA |
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REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Signal Transduction | R-HSA-162582 | 1.78 |
Axonal growth inhibition (RHOA activation) | R-HSA-193634 | 9.81 |
Signalling by NGF | R-HSA-166520 | 4.23 |
p75 NTR receptor-mediated signalling | R-HSA-193704 | 6.59 |
p75NTR regulates axonogenesis | R-HSA-193697 | 9.66 |
GO term | GO ID | GO IC |
---|---|---|
neuregulin receptor activity | GO:0038131 | 9.74 |
kinase inhibitor activity | GO:0019210 | 5.25 |
signaling receptor activity | GO:0038023 | 2.49 |
kinase regulator activity | GO:0019207 | 4.5 |
protein binding | GO:0005515 | 0.46 |
protein kinase regulator activity | GO:0019887 | 4.6 |
enzyme regulator activity | GO:0030234 | 2.85 |
protein kinase inhibitor activity | GO:0004860 | 5.28 |
molecular transducer activity | GO:0060089 | 2.32 |
transmembrane signaling receptor activity | GO:0004888 | 2.57 |
binding | GO:0005488 | 0.18 |
signal transducer activity | GO:0004871 | 2.28 |
enzyme inhibitor activity | GO:0004857 | 3.78 |
molecular function regulator | GO:0098772 | 2.51 |
transmembrane receptor activity | GO:0099600 | 2.53 |
receptor activity | GO:0004872 | 2.32 |