Disease ID | Disease name | Source of annotation with S1PR2 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
PS220290 | DEAFNESS, AUTOSOMAL RECESSIVE | ClinVar, OMIM | link to OMIM | 60 | CLIC5, KARS, OTOGL, CABP2, HGF, DFNB59, GIPC3, EPS8, MYO3A, CDH23, OTOF, ELMOD3, ESRRB, RDX, GJB2, GJB3, ESPN, ADCY1, CIB2, STRC, TMIE, S1PR2, FAM65B, TSPEAR, TBC1D24, SLC26A4, OTOG, COL11A2, MARVELD2, PNPT1, MYO15A, WHRN, CLDN14, MYO7A, GJB6, MET, TPRN, DCDC2, LRTOMT, TMC1, MYO6, ILDR1, MSRB3, SERPINB6, SLC26A5, ATP2B2, LHFPL5, SYNE4, GRXCR2, FOXI1, GRXCR1, LOXHD1, TECTA, PCDH15, TRIOBP, USH1C, KCNJ10, PTPRQ, TMPRSS3, OTOA |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Neuroactive ligand-receptor interaction | hsa04080 | 4.58 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Signaling by GPCR | R-HSA-372790 | 2.68 |
G alpha (i) signalling events | R-HSA-418594 | 5.1 |
Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 4.69 |
Lysosphingolipid and LPA receptors | R-HSA-419408 | 9.81 |
GPCR downstream signaling | R-HSA-388396 | 3.07 |
GPCR ligand binding | R-HSA-500792 | 4.19 |
Signal Transduction | R-HSA-162582 | 1.78 |
GO term | GO ID | GO IC |
---|---|---|
integrin binding | GO:0005178 | 5.07 |
G-protein coupled receptor activity | GO:0004930 | 2.95 |
signaling receptor activity | GO:0038023 | 2.49 |
signal transducer activity | GO:0004871 | 2.28 |
sphingosine-1-phosphate receptor activity | GO:0038036 | 7.66 |
lipid binding | GO:0008289 | 3.26 |
bioactive lipid receptor activity | GO:0045125 | 7.1 |
molecular transducer activity | GO:0060089 | 2.32 |
transmembrane signaling receptor activity | GO:0004888 | 2.57 |
macromolecular complex binding | GO:0044877 | 2.61 |
receptor activity | GO:0004872 | 2.32 |
protein binding | GO:0005515 | 0.46 |
protein complex binding | GO:0032403 | 3.09 |
G-protein coupled receptor binding | GO:0001664 | 4.18 |
receptor binding | GO:0005102 | 2.43 |
cell adhesion molecule binding | GO:0050839 | 4.5 |
transmembrane receptor activity | GO:0099600 | 2.53 |
binding | GO:0005488 | 0.18 |