Disease ID | Disease name | Source of annotation with SH2D1A | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
PS308240 | LYMPHOPROLIFERATIVE SYNDROME | ClinVar, OMIM, HUMSAVAR | link to OMIM | 4 | ITK, SH2D1A, CD27, XIAP |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Natural killer cell mediated cytotoxicity | hsa04650 | 5.53 |
Measles | hsa05162 | 5.6 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Immune System | R-HSA-168256 | 2.37 |
Adaptive Immune System | R-HSA-1280218 | 3.19 |
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 4.7 |
GO term | GO ID | GO IC |
---|---|---|
SH3/SH2 adaptor activity | GO:0005070 | 5.79 |
protein binding, bridging | GO:0030674 | 4.68 |
signaling adaptor activity | GO:0035591 | 5.43 |
binding | GO:0005488 | 0.18 |
protein binding | GO:0005515 | 0.46 |
binding, bridging | GO:0060090 | 4.57 |