Gene table of SLC1A4 : solute carrier family 1 member 4

Gene-disease associations table

Disease ID	Disease name	Source of annotation with SLC1A4	OMIM link	Number of associated genes	genes
616657	SPASTIC TETRAPLEGIA, THIN CORPUS CALLOSUM, AND PROGRESSIVE MICROCEPHALY	OMIM, HUMSAVAR	link to OMIM	1	SLC1A4

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Annotation of the gene SLC1A4

Associated genes in ENSEMBL

ENSG00000115902

Associated proteins - SwissProt Accession ID

P43007

Associated PDB IDs

Cytogenetic Band

2p14

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

CREB3L1

Associated KEGG pathways

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
SLC-mediated transmembrane transport	R-HSA-425407	4.95
Transport of inorganic cations/anions and amino acids/oligopeptides	R-HSA-425393	6.41
Amino acid transport across the plasma membrane	R-HSA-352230	8.03
Transmembrane transport of small molecules	R-HSA-382551	3.79

Associated GO terms for Molecular function

GO term	GO ID	GO IC
organic acid transmembrane transporter activity	GO:0005342	4.97
L-cystine transmembrane transporter activity	GO:0015184	8.35
secondary active transmembrane transporter activity	GO:0015291	4.29
L-glutamine transmembrane transporter activity	GO:0015186	8.13
L-alanine transmembrane transporter activity	GO:0015180	7.79
sulfur compound transmembrane transporter activity	GO:1901682	6.44
anion transmembrane transporter activity	GO:0008509	4.43
serine transmembrane transporter activity	GO:0022889	7.54
inorganic anion transmembrane transporter activity	GO:0015103	4.87
passive transmembrane transporter activity	GO:0022803	3.6
anion channel activity	GO:0005253	5.23
chloride channel activity	GO:0005254	5.36
chloride transmembrane transporter activity	GO:0015108	5.24
active transmembrane transporter activity	GO:0022804	3.85
sulfur amino acid transmembrane transporter activity	GO:0000099	7.79
symporter activity	GO:0015293	4.78
transporter activity	GO:0005215	2.57
ion channel activity	GO:0005216	3.71
L-hydroxyproline transmembrane transporter activity	GO:0034590	9.74
L-serine transmembrane transporter activity	GO:0015194	7.54
L-threonine transmembrane transporter activity	GO:0015195	9.74
L-proline transmembrane transporter activity	GO:0015193	7.79
carboxylic acid transmembrane transporter activity	GO:0046943	4.99
substrate-specific transmembrane transporter activity	GO:0022891	2.9
substrate-specific transporter activity	GO:0022892	2.72
modified amino acid transmembrane transporter activity	GO:0072349	6.97
amino acid transmembrane transporter activity	GO:0015171	5.38
ion transmembrane transporter activity	GO:0015075	3.04
transmembrane transporter activity	GO:0022857	2.82
channel activity	GO:0015267	3.6
L-amino acid transmembrane transporter activity	GO:0015179	6.0
neutral amino acid transmembrane transporter activity	GO:0015175	6.24
substrate-specific channel activity	GO:0022838	3.67
alanine transmembrane transporter activity	GO:0022858	7.79