Disease ID | Disease name | Source of annotation with SLC2A2 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
227810 | FANCONI-BICKEL SYNDROME | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | SLC2A2 |
125853 | DIABETES MELLITUS, NONINSULIN-DEPENDENT | ClinVar, OMIM | link to OMIM | 33 | SLC2A2, HNF4A, TCF7L2, SLC30A8, GPD2, PAX4, PTPN1, SLC2A4, ABCC8, HMGA1, LIPC, NEUROD1, CDKAL1, WFS1, PPARG, RETN, AKT2, IRS2, IL6, IRS1, GCGR, CAPN10, IGF2BP2, INSR, PDX1, MTNR1B, GCK, HNF1B, HNF1A, MAPK8IP1, ENPP1, PPP1R3A, KCNJ11 |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Carbohydrate digestion and absorption | hsa04973 | 7.28 |
Maturity onset diabetes of the young | hsa04950 | 8.07 |
Insulin secretion | hsa04911 | 6.18 |
Central carbon metabolism in cancer | hsa05230 | 6.7 |
Prolactin signaling pathway | hsa04917 | 6.6 |
Type II diabetes mellitus | hsa04930 | 7.12 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Facilitative Na+-independent glucose transporters | R-HSA-428790 | 9.28 |
Regulation of gene expression in beta cells | R-HSA-210745 | 8.66 |
Regulation of insulin secretion | R-HSA-422356 | 6.66 |
Regulation of beta-cell development | R-HSA-186712 | 7.98 |
Integration of energy metabolism | R-HSA-163685 | 6.24 |
Transmembrane transport of small molecules | R-HSA-382551 | 3.79 |
Hexose transport | R-HSA-189200 | 7.43 |
Metabolism | R-HSA-1430728 | 2.34 |
SLC-mediated transmembrane transport | R-HSA-425407 | 4.95 |
Glucose transport | R-HSA-70153 | 7.62 |
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | R-HSA-425366 | 6.34 |
Developmental Biology | R-HSA-1266738 | 3.48 |
Metabolism of carbohydrates | R-HSA-71387 | 4.93 |
GO term | GO ID | GO IC |
---|---|---|
substrate-specific transmembrane transporter activity | GO:0022891 | 2.9 |
glucose transmembrane transporter activity | GO:0005355 | 6.85 |
substrate-specific transporter activity | GO:0022892 | 2.72 |
vitamin transporter activity | GO:0051183 | 6.56 |
sugar transmembrane transporter activity | GO:0051119 | 6.3 |
carbohydrate transporter activity | GO:1901476 | 5.95 |
transporter activity | GO:0005215 | 2.57 |
insulin receptor binding | GO:0005158 | 6.27 |
D-glucose transmembrane transporter activity | GO:0055056 | 7.66 |
hexose transmembrane transporter activity | GO:0015149 | 6.79 |
transmembrane transporter activity | GO:0022857 | 2.82 |
macromolecular complex binding | GO:0044877 | 2.61 |
binding | GO:0005488 | 0.18 |
protein binding | GO:0005515 | 0.46 |
protein complex binding | GO:0032403 | 3.09 |
receptor binding | GO:0005102 | 2.43 |
dehydroascorbic acid transporter activity | GO:0033300 | 8.35 |
monosaccharide transmembrane transporter activity | GO:0015145 | 6.79 |
carbohydrate transmembrane transporter activity | GO:0015144 | 5.95 |