Gene table of SLC2A2 : solute carrier family 2 member 2

Gene-disease associations table

Disease IDDisease nameSource of annotation with SLC2A2OMIM linkNumber of associated genesgenes
227810FANCONI-BICKEL SYNDROMEClinVar, OMIM, HUMSAVAR link to OMIM 1SLC2A2
125853DIABETES MELLITUS, NONINSULIN-DEPENDENTClinVar, OMIM link to OMIM 33SLC2A2, HNF4A, TCF7L2, SLC30A8, GPD2, PAX4, PTPN1, SLC2A4, ABCC8, HMGA1, LIPC, NEUROD1, CDKAL1, WFS1, PPARG, RETN, AKT2, IRS2, IL6, IRS1, GCGR, CAPN10, IGF2BP2, INSR, PDX1, MTNR1B, GCK, HNF1B, HNF1A, MAPK8IP1, ENPP1, PPP1R3A, KCNJ11

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Annotation of the gene SLC2A2

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Carbohydrate digestion and absorptionhsa049737.28
Maturity onset diabetes of the younghsa049508.07
Insulin secretionhsa049116.18
Central carbon metabolism in cancerhsa052306.7
Prolactin signaling pathwayhsa049176.6
Type II diabetes mellitushsa049307.12
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Facilitative Na+-independent glucose transportersR-HSA-4287909.28
Regulation of gene expression in beta cellsR-HSA-2107458.66
Regulation of insulin secretionR-HSA-4223566.66
Regulation of beta-cell developmentR-HSA-1867127.98
Integration of energy metabolismR-HSA-1636856.24
Transmembrane transport of small moleculesR-HSA-3825513.79
Hexose transportR-HSA-1892007.43
MetabolismR-HSA-14307282.34
SLC-mediated transmembrane transportR-HSA-4254074.95
Glucose transportR-HSA-701537.62
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsR-HSA-4253666.34
Developmental BiologyR-HSA-12667383.48
Metabolism of carbohydratesR-HSA-713874.93
Associated GO terms for Molecular function
GO termGO IDGO IC
substrate-specific transmembrane transporter activityGO:00228912.9
glucose transmembrane transporter activityGO:00053556.85
substrate-specific transporter activityGO:00228922.72
vitamin transporter activityGO:00511836.56
sugar transmembrane transporter activityGO:00511196.3
carbohydrate transporter activityGO:19014765.95
transporter activityGO:00052152.57
insulin receptor bindingGO:00051586.27
D-glucose transmembrane transporter activityGO:00550567.66
hexose transmembrane transporter activityGO:00151496.79
transmembrane transporter activityGO:00228572.82
macromolecular complex bindingGO:00448772.61
bindingGO:00054880.18
protein bindingGO:00055150.46
protein complex bindingGO:00324033.09
receptor bindingGO:00051022.43
dehydroascorbic acid transporter activityGO:00333008.35
monosaccharide transmembrane transporter activityGO:00151456.79
carbohydrate transmembrane transporter activityGO:00151445.95