Gene table of SLC2A4 : solute carrier family 2 member 4

Gene-disease associations table

Disease IDDisease nameSource of annotation with SLC2A4OMIM linkNumber of associated genesgenes
125853DIABETES MELLITUS, NONINSULIN-DEPENDENTClinVar, HUMSAVAR link to OMIM 33SLC2A2, HNF4A, TCF7L2, SLC30A8, GPD2, PAX4, PTPN1, SLC2A4, ABCC8, HMGA1, LIPC, NEUROD1, CDKAL1, WFS1, PPARG, RETN, AKT2, IRS2, IL6, IRS1, GCGR, CAPN10, IGF2BP2, INSR, PDX1, MTNR1B, GCK, HNF1B, HNF1A, MAPK8IP1, ENPP1, PPP1R3A, KCNJ11

Download the gene annotation in CSV format

Annotation of the gene SLC2A4

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Type II diabetes mellitushsa049307.12
Insulin signaling pathwayhsa049105.55
AMPK signaling pathwayhsa041525.8
FoxO signaling pathwayhsa040685.63
Adipocytokine signaling pathwayhsa049206.6
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Facilitative Na+-independent glucose transportersR-HSA-4287909.28
Membrane TraffickingR-HSA-1999915.26
Metabolism of carbohydratesR-HSA-713874.93
Transcriptional regulation of white adipocyte differentiationR-HSA-3813406.7
Transmembrane transport of small moleculesR-HSA-3825513.79
Hexose transportR-HSA-1892007.43
MetabolismR-HSA-14307282.34
SLC-mediated transmembrane transportR-HSA-4254074.95
Translocation of GLUT4 to the plasma membraneR-HSA-14451486.77
Glucose transportR-HSA-701537.62
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsR-HSA-4253666.34
Developmental BiologyR-HSA-12667383.48
Vesicle-mediated transportR-HSA-56536564.33
Associated GO terms for Molecular function
GO termGO IDGO IC
substrate-specific transmembrane transporter activityGO:00228912.9
glucose transmembrane transporter activityGO:00053556.85
substrate-specific transporter activityGO:00228922.72
sugar transmembrane transporter activityGO:00511196.3
carbohydrate transporter activityGO:19014765.95
transporter activityGO:00052152.57
D-glucose transmembrane transporter activityGO:00550567.66
hexose transmembrane transporter activityGO:00151496.79
transmembrane transporter activityGO:00228572.82
bindingGO:00054880.18
protein bindingGO:00055150.46
monosaccharide transmembrane transporter activityGO:00151456.79
carbohydrate transmembrane transporter activityGO:00151445.95