Gene table of SLC40A1 : solute carrier family 40 member 1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with SLC40A1	OMIM link	Number of associated genes	genes
PS235200	HEMOCHROMATOSIS	ClinVar, OMIM, HUMSAVAR	link to OMIM	7	TFR2, HAMP, FTH1, BMP2, HFE2, SLC40A1, HFE

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Mineral absorption	hsa04978	7.09

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
SLC-mediated transmembrane transport	R-HSA-425407	4.95
Metal ion SLC transporters	R-HSA-425410	8.34
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds	R-HSA-425366	6.34
Iron uptake and transport	R-HSA-917937	7.56
Transmembrane transport of small molecules	R-HSA-382551	3.79

Associated GO terms for Molecular function

GO term	GO ID	GO IC
peptide hormone binding	GO:0017046	6.13
cation channel activity	GO:0005261	4.04
molecular transducer activity	GO:0060089	2.32
receptor activity	GO:0004872	2.32
peptide binding	GO:0042277	4.22
transition metal ion transmembrane transporter activity	GO:0046915	6.05
divalent inorganic cation transmembrane transporter activity	GO:0072509	4.62
iron ion transmembrane transporter activity	GO:0005381	7.66
transporter activity	GO:0005215	2.57
passive transmembrane transporter activity	GO:0022803	3.6
metal ion transmembrane transporter activity	GO:0046873	3.71
amide binding	GO:0033218	4.14
ion channel activity	GO:0005216	3.71
cation transmembrane transporter activity	GO:0008324	3.32
ferrous iron transmembrane transporter activity	GO:0015093	8.64
hormone binding	GO:0042562	5.53
substrate-specific transmembrane transporter activity	GO:0022891	2.9
inorganic cation transmembrane transporter activity	GO:0022890	3.49
substrate-specific transporter activity	GO:0022892	2.72
ion transmembrane transporter activity	GO:0015075	3.04
transmembrane transporter activity	GO:0022857	2.82
channel activity	GO:0015267	3.6
iron channel activity	GO:0097689	9.74
protein binding	GO:0005515	0.46
substrate-specific channel activity	GO:0022838	3.67
binding	GO:0005488	0.18