Gene table of SLC46A1 : solute carrier family 46 member 1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with SLC46A1	OMIM link	Number of associated genes	genes
229050	FOLATE MALABSORPTION, HEREDITARY	OMIM, HUMSAVAR	link to OMIM	1	SLC46A1

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Mineral absorption	hsa04978	7.09
Vitamin digestion and absorption	hsa04977	8.24

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Metabolism of folate and pterines	R-HSA-196757	9.81
Metabolism of vitamins and cofactors	R-HSA-196854	6.54
Iron uptake and transport	R-HSA-917937	7.56
Metabolism	R-HSA-1430728	2.34
Transmembrane transport of small molecules	R-HSA-382551	3.79
Metabolism of water-soluble vitamins and cofactors	R-HSA-196849	6.54

Associated GO terms for Molecular function

GO term	GO ID	GO IC
binding	GO:0005488	0.18
heterocyclic compound binding	GO:1901363	1.06
cofactor transporter activity	GO:0051184	6.69
heme transporter activity	GO:0015232	7.66
vitamin transporter activity	GO:0051183	6.56
folic acid binding	GO:0005542	7.17
monovalent inorganic cation transmembrane transporter activity	GO:0015077	3.87
methotrexate transporter activity	GO:0015350	9.05
amide binding	GO:0033218	4.14
transporter activity	GO:0005215	2.57
cation transmembrane transporter activity	GO:0008324	3.32
small molecule binding	GO:0036094	1.89
substrate-specific transmembrane transporter activity	GO:0022891	2.9
inorganic cation transmembrane transporter activity	GO:0022890	3.49
substrate-specific transporter activity	GO:0022892	2.72
modified amino acid binding	GO:0072341	5.56
organic acid binding	GO:0043177	6.6
organic cyclic compound binding	GO:0097159	1.05
folic acid transporter activity	GO:0008517	7.79
vitamin binding	GO:0019842	5.34
ion transmembrane transporter activity	GO:0015075	3.04
transmembrane transporter activity	GO:0022857	2.82
drug transporter activity	GO:0090484	6.69
hydrogen ion transmembrane transporter activity	GO:0015078	5.01