Gene table of SMAD1

No gene-disease associations

Annotation of the gene SMAD1

Associated genes in ENSEMBL

ENSG00000170365

Associated proteins - SwissProt Accession ID

Q15797

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

It is a TF of the genes:

It is regulated by the following TF:

GATA1

Associated KEGG pathways

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
nucleic acid binding	GO:0003676	1.44
RNA polymerase II regulatory region DNA binding	GO:0001012	3.36
core promoter proximal region DNA binding	GO:0001159	3.82
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	GO:0001077	4.31
binding	GO:0005488	0.18
signal transducer activity	GO:0004871	2.28
DNA binding	GO:0003677	1.92
heterocyclic compound binding	GO:1901363	1.06
sequence-specific DNA binding	GO:0043565	2.79
transforming growth factor beta receptor, cytoplasmic mediator activity	GO:0005072	7.44
sequence-specific double-stranded DNA binding	GO:1990837	3.2
transcription regulatory region DNA binding	GO:0044212	3.03
receptor signaling protein activity	GO:0005057	4.76
ion binding	GO:0043167	1.36
identical protein binding	GO:0042802	2.63
co-SMAD binding	GO:0070410	7.25
I-SMAD binding	GO:0070411	7.34
core promoter proximal region sequence-specific DNA binding	GO:0000987	3.83
double-stranded DNA binding	GO:0003690	3.09
metal ion binding	GO:0046872	1.41
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding	GO:0000982	3.94
RNA polymerase II transcription factor activity, sequence-specific DNA binding	GO:0000981	3.29
protein homodimerization activity	GO:0042803	3.16
cation binding	GO:0043169	1.4
regulatory region nucleic acid binding	GO:0001067	3.03
protein kinase binding	GO:0019901	3.44
kinase binding	GO:0019900	3.32
enzyme binding	GO:0019899	2.27
core promoter binding	GO:0001047	4.71
core promoter sequence-specific DNA binding	GO:0001046	5.12
RNA polymerase II core promoter proximal region sequence-specific DNA binding	GO:0000978	3.88
SMAD binding	GO:0046332	5.45
protein heterodimerization activity	GO:0046982	3.64
transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity	GO:0030618	8.13
transcription factor activity, sequence-specific DNA binding	GO:0003700	2.65
organic cyclic compound binding	GO:0097159	1.05
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	GO:0001228	3.98
transcription regulatory region sequence-specific DNA binding	GO:0000976	3.24
RNA polymerase II regulatory region sequence-specific DNA binding	GO:0000977	3.37
protein binding	GO:0005515	0.46
regulatory region DNA binding	GO:0000975	3.03
protein dimerization activity	GO:0046983	2.72
RNA polymerase II core promoter sequence-specific DNA binding	GO:0000979	5.77
nucleic acid binding transcription factor activity	GO:0001071	2.65