Gene table of SMC3 : structural maintenance of chromosomes 3

Gene-disease associations table

Disease IDDisease nameSource of annotation with SMC3OMIM linkNumber of associated genesgenes
PS122470CORNELIA DE LANGE SYNDROMEClinVar, OMIM link to OMIM 7RAD21, TAF6, HDAC8, KMT2A, SMC1A, SMC3, NIPBL

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Annotation of the gene SMC3

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Cell cyclehsa041105.68
Oocyte meiosishsa041145.91
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
SUMOylationR-HSA-29908466.68
Mitotic Telophase/CytokinesisR-HSA-688849.18
Resolution of Sister Chromatid CohesionR-HSA-25002576.18
Establishment of Sister Chromatid CohesionR-HSA-24680529.52
Separation of Sister ChromatidsR-HSA-24678135.55
M PhaseR-HSA-688864.87
SUMO E3 ligases SUMOylate target proteinsR-HSA-31082326.77
Metabolism of proteinsR-HSA-3924993.41
Mitotic Metaphase and AnaphaseR-HSA-25553965.45
S PhaseR-HSA-692426.02
MeiosisR-HSA-15006206.59
Cell Cycle, MitoticR-HSA-692784.16
Meiotic synapsisR-HSA-12216327.18
Mitotic AnaphaseR-HSA-688825.46
SUMOylation of DNA damage response and repair proteinsR-HSA-31082146.77
Cell CycleR-HSA-16401703.89
Post-translational protein modificationR-HSA-5975924.54
Mitotic PrometaphaseR-HSA-688776.08
Cohesin Loading onto ChromatinR-HSA-24709469.66
Associated GO terms for Molecular function
GO termGO IDGO IC
purine ribonucleoside triphosphate bindingGO:00356392.22
macromolecular complex bindingGO:00448772.61
bindingGO:00054880.18
heterocyclic compound bindingGO:19013631.06
nucleoside phosphate bindingGO:19012651.96
nucleoside bindingGO:00018822.21
dynein bindingGO:00455026.44
nucleotide bindingGO:00001661.96
purine nucleoside bindingGO:00018832.22
ribonucleoside bindingGO:00325492.22
protein complex bindingGO:00324033.09
purine nucleotide bindingGO:00170762.19
motor activityGO:00037744.81
microtubule motor activityGO:00037775.34
hydrolase activityGO:00167871.9
nucleoside-triphosphatase activityGO:00171113.09
small molecule bindingGO:00360941.89
catalytic activityGO:00038241.05
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:00168183.03
protein heterodimerization activityGO:00469823.64
adenyl nucleotide bindingGO:00305542.4
carbohydrate derivative bindingGO:00973672.03
organic cyclic compound bindingGO:00971591.05
hydrolase activity, acting on acid anhydridesGO:00168173.03
pyrophosphatase activityGO:00164623.04
adenyl ribonucleotide bindingGO:00325592.41
ATP bindingGO:00055242.43
protein bindingGO:00055150.46
mediator complex bindingGO:00360338.35
purine ribonucleotide bindingGO:00325552.2
protein dimerization activityGO:00469832.72
chromatin bindingGO:00036823.64
purine ribonucleoside bindingGO:00325502.22
ribonucleotide bindingGO:00325532.19