Gene table of SOX17 : SRY-box 17

Gene-disease associations table

Disease ID	Disease name	Source of annotation with SOX17	OMIM link	Number of associated genes	genes
PS193000	VESICOURETERAL REFLUX	ClinVar, OMIM, HUMSAVAR	link to OMIM	3	SOX17, TNXB, ROBO2

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Wnt signaling pathway	hsa04310	5.49

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
TCF dependent signaling in response to WNT	R-HSA-201681	5.36
Signaling by Wnt	R-HSA-195721	4.79
Signal Transduction	R-HSA-162582	1.78
deactivation of the beta-catenin transactivating complex	R-HSA-3769402	7.59

Associated GO terms for Molecular function

GO term	GO ID	GO IC
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	GO:0001228	3.98
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
DNA binding	GO:0003677	1.92
heterocyclic compound binding	GO:1901363	1.06
sequence-specific DNA binding	GO:0043565	2.79
transcription coactivator activity	GO:0003713	4.04
transcription cofactor activity	GO:0003712	3.44
transcription factor activity, transcription factor binding	GO:0000989	3.36
transcription factor activity, protein binding	GO:0000988	3.35
RNA polymerase II transcription factor activity, sequence-specific DNA binding	GO:0000981	3.29
transcription factor binding	GO:0008134	3.46
regulatory region nucleic acid binding	GO:0001067	3.03
beta-catenin binding	GO:0008013	5.3
transcription regulatory region DNA binding	GO:0044212	3.03
transcription factor activity, sequence-specific DNA binding	GO:0003700	2.65
organic cyclic compound binding	GO:0097159	1.05
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding	GO:0003705	5.23
protein binding	GO:0005515	0.46
regulatory region DNA binding	GO:0000975	3.03
protein dimerization activity	GO:0046983	2.72
protein heterodimerization activity	GO:0046982	3.64
nucleic acid binding transcription factor activity	GO:0001071	2.65