Disease ID | Disease name | Source of annotation with ST3GAL3 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
PS308350 | EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE | ClinVar, OMIM, HUMSAVAR | link to OMIM | 37 | SZT2, EEF1A2, KCNT1, ALG13, ST3GAL3, WWOX, ITPA, SIK1, SCN1A, ARHGEF9, GNAO1, TBC1D24, DNM1, SLC35A2, SCN8A, SLC13A5, SLC25A22, HCN1, KCNB1, STXBP1, SCN9A, CDKL5, KCNQ2, SPTAN1, KCNA2, SCN2A, PLCB1, AARS, PCDH19, PNKP, SLC12A5, GABRA1, DOCK7, ARX, GRIN2B, NECAP1, PIGA |
PS249500 | MENTAL RETARDATION, AUTOSOMAL RECESSIVE | ClinVar, OMIM, HUMSAVAR | link to OMIM | 31 | ADAT3, NDST1, GPT2, PIGG, FMN2, TTI2, PGAP1, HNMT, EDC3, NSUN2, KPTN, GRIK2, TAF2, KIAA1033, MED23, PRSS12, FBXO31, LINS1, HERC2, CC2D1A, METTL23, TUSC3, ST3GAL3, TECR, CRADD, MAN1B1, SLC6A17, ANK3, CRBN, TRAPPC9, LMAN2L |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Metabolic pathways | hsa01100 | 2.49 |
Glycosphingolipid biosynthesis - lacto and neolacto series | hsa00601 | 7.86 |
Other types of O-glycan biosynthesis | hsa00514 | 7.72 |
Glycosaminoglycan biosynthesis - keratan sulfate | hsa00533 | 8.68 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Keratan sulfate biosynthesis | R-HSA-2022854 | 8.18 |
Synthesis of substrates in N-glycan biosythesis | R-HSA-446219 | 7.28 |
Metabolism of carbohydrates | R-HSA-71387 | 4.93 |
Keratan sulfate/keratin metabolism | R-HSA-1638074 | 7.89 |
Glycosaminoglycan metabolism | R-HSA-1630316 | 6.04 |
Metabolism of proteins | R-HSA-392499 | 3.41 |
Sialic acid metabolism | R-HSA-4085001 | 7.94 |
Asparagine N-linked glycosylation | R-HSA-446203 | 6.1 |
Signaling by NOTCH | R-HSA-157118 | 6.2 |
Metabolism | R-HSA-1430728 | 2.34 |
Termination of O-glycan biosynthesis | R-HSA-977068 | 8.28 |
O-linked glycosylation | R-HSA-5173105 | 6.3 |
Pre-NOTCH Processing in Golgi | R-HSA-1912420 | 8.81 |
Post-translational protein modification | R-HSA-597592 | 4.54 |
Pre-NOTCH Expression and Processing | R-HSA-1912422 | 7.49 |
O-linked glycosylation of mucins | R-HSA-913709 | 6.98 |
Signal Transduction | R-HSA-162582 | 1.78 |
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | R-HSA-446193 | 6.92 |
GO term | GO ID | GO IC |
---|---|---|
N-acetyllactosaminide alpha-2,3-sialyltransferase activity | GO:0008118 | 9.74 |
beta-galactoside (CMP) alpha-2,3-sialyltransferase activity | GO:0003836 | 7.79 |
catalytic activity | GO:0003824 | 1.05 |
transferase activity | GO:0016740 | 1.95 |
transferase activity, transferring glycosyl groups | GO:0016757 | 4.08 |
sialyltransferase activity | GO:0008373 | 6.69 |