Gene table of ST3GAL3 : ST3 beta-galactoside alpha-2,3-sialyltransferase 3

Gene-disease associations table

Disease IDDisease nameSource of annotation with ST3GAL3OMIM linkNumber of associated genesgenes
PS308350EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILEClinVar, OMIM, HUMSAVAR link to OMIM 37SZT2, EEF1A2, KCNT1, ALG13, ST3GAL3, WWOX, ITPA, SIK1, SCN1A, ARHGEF9, GNAO1, TBC1D24, DNM1, SLC35A2, SCN8A, SLC13A5, SLC25A22, HCN1, KCNB1, STXBP1, SCN9A, CDKL5, KCNQ2, SPTAN1, KCNA2, SCN2A, PLCB1, AARS, PCDH19, PNKP, SLC12A5, GABRA1, DOCK7, ARX, GRIN2B, NECAP1, PIGA
PS249500MENTAL RETARDATION, AUTOSOMAL RECESSIVEClinVar, OMIM, HUMSAVAR link to OMIM 31ADAT3, NDST1, GPT2, PIGG, FMN2, TTI2, PGAP1, HNMT, EDC3, NSUN2, KPTN, GRIK2, TAF2, KIAA1033, MED23, PRSS12, FBXO31, LINS1, HERC2, CC2D1A, METTL23, TUSC3, ST3GAL3, TECR, CRADD, MAN1B1, SLC6A17, ANK3, CRBN, TRAPPC9, LMAN2L

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Annotation of the gene ST3GAL3

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Metabolic pathwayshsa011002.49
Glycosphingolipid biosynthesis - lacto and neolacto serieshsa006017.86
Other types of O-glycan biosynthesishsa005147.72
Glycosaminoglycan biosynthesis - keratan sulfatehsa005338.68
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Keratan sulfate biosynthesisR-HSA-20228548.18
Synthesis of substrates in N-glycan biosythesisR-HSA-4462197.28
Metabolism of carbohydratesR-HSA-713874.93
Keratan sulfate/keratin metabolismR-HSA-16380747.89
Glycosaminoglycan metabolismR-HSA-16303166.04
Metabolism of proteinsR-HSA-3924993.41
Sialic acid metabolismR-HSA-40850017.94
Asparagine N-linked glycosylationR-HSA-4462036.1
Signaling by NOTCHR-HSA-1571186.2
MetabolismR-HSA-14307282.34
Termination of O-glycan biosynthesisR-HSA-9770688.28
O-linked glycosylationR-HSA-51731056.3
Pre-NOTCH Processing in GolgiR-HSA-19124208.81
Post-translational protein modificationR-HSA-5975924.54
Pre-NOTCH Expression and ProcessingR-HSA-19124227.49
O-linked glycosylation of mucinsR-HSA-9137096.98
Signal TransductionR-HSA-1625821.78
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent proteinR-HSA-4461936.92
Associated GO terms for Molecular function
GO termGO IDGO IC
N-acetyllactosaminide alpha-2,3-sialyltransferase activityGO:00081189.74
beta-galactoside (CMP) alpha-2,3-sialyltransferase activityGO:00038367.79
catalytic activityGO:00038241.05
transferase activityGO:00167401.95
transferase activity, transferring glycosyl groupsGO:00167574.08
sialyltransferase activityGO:00083736.69