Disease ID | Disease name | Source of annotation with TBXA2R | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
PS231200 | BLEEDING DISORDER, PLATELET-TYPE | ClinVar, OMIM, HUMSAVAR | link to OMIM | 21 | NBEAL2, ANO6, GP1BA, ITGA2, GFI1B, ITGA2B, PLAU, PRKACG, P2RY12, ACTN1, TBXAS1, P2RX1, GP6, CD36, SLFN14, ITGB3, GP9, GP1BB, RASGRP2, TBXA2R, MYH9 |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Platelet activation | hsa04611 | 5.66 |
Calcium signaling pathway | hsa04020 | 5.22 |
Neuroactive ligand-receptor interaction | hsa04080 | 4.58 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
GPCR ligand binding | R-HSA-500792 | 4.19 |
Signaling by GPCR | R-HSA-372790 | 2.68 |
G alpha (12/13) signalling events | R-HSA-416482 | 6.75 |
GPCR downstream signaling | R-HSA-388396 | 3.07 |
Platelet activation, signaling and aggregation | R-HSA-76002 | 5.15 |
Gastrin-CREB signalling pathway via PKC and MAPK | R-HSA-881907 | 4.26 |
Thromboxane signalling through TP receptor | R-HSA-428930 | 8.46 |
G alpha (q) signalling events | R-HSA-416476 | 5.42 |
Prostanoid ligand receptors | R-HSA-391908 | 9.81 |
Signal amplification | R-HSA-392518 | 7.98 |
Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 4.69 |
Eicosanoid ligand-binding receptors | R-HSA-391903 | 9.08 |
Hemostasis | R-HSA-109582 | 3.98 |
Signal Transduction | R-HSA-162582 | 1.78 |
GO term | GO ID | GO IC |
---|---|---|
G-protein coupled receptor activity | GO:0004930 | 2.95 |
signaling receptor activity | GO:0038023 | 2.49 |
signal transducer activity | GO:0004871 | 2.28 |
guanyl-nucleotide exchange factor activity | GO:0005085 | 4.02 |
molecular transducer activity | GO:0060089 | 2.32 |
transmembrane signaling receptor activity | GO:0004888 | 2.57 |
icosanoid receptor activity | GO:0004953 | 7.03 |
prostanoid receptor activity | GO:0004954 | 7.44 |
receptor activity | GO:0004872 | 2.32 |
protein binding | GO:0005515 | 0.46 |
molecular function regulator | GO:0098772 | 2.51 |
thromboxane A2 receptor activity | GO:0004961 | 9.74 |
thromboxane receptor activity | GO:0004960 | 9.74 |
transmembrane receptor activity | GO:0099600 | 2.53 |
binding | GO:0005488 | 0.18 |