| Disease ID | Disease name | Source of annotation with THBS4 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS142623 | HIRSCHSPRUNG DISEASE | ClinVar | link to OMIM | 21 | TSC2, KDR, GDNF, PTCH1, GFRA1, NTF3, IRAK3, EDN3, ZHX2, THBS4, AHNAK, POLR2F, FBN1, RET, CNTN5, DPYD, EDNRB, CREBBP, SEMA3D, FAT3, PLAU |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| ECM-receptor interaction | hsa04512 | 6.09 |
| Phagosome | hsa04145 | 5.27 |
| Malaria | hsa05144 | 7.15 |
| Focal adhesion | hsa04510 | 4.92 |
| PI3K-Akt signaling pathway | hsa04151 | 4.21 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Signaling by PDGF | R-HSA-186797 | 4.53 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| GO term | GO ID | GO IC |
|---|---|---|
| sulfur compound binding | GO:1901681 | 4.32 |
| cation binding | GO:0043169 | 1.4 |
| laminin binding | GO:0043236 | 6.34 |
| laminin-1 binding | GO:0043237 | 7.79 |
| growth factor activity | GO:0008083 | 4.66 |
| extracellular matrix binding | GO:0050840 | 5.79 |
| carbohydrate derivative binding | GO:0097367 | 2.03 |
| collagen binding | GO:0005518 | 5.58 |
| integrin binding | GO:0005178 | 5.07 |
| ion binding | GO:0043167 | 1.36 |
| glycosaminoglycan binding | GO:0005539 | 4.42 |
| cell adhesion molecule binding | GO:0050839 | 4.5 |
| macromolecular complex binding | GO:0044877 | 2.61 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| protein complex binding | GO:0032403 | 3.09 |
| receptor binding | GO:0005102 | 2.43 |
| metal ion binding | GO:0046872 | 1.41 |
| heparin binding | GO:0008201 | 4.68 |
| fibronectin binding | GO:0001968 | 6.41 |
| calcium ion binding | GO:0005509 | 3.17 |