Gene table of TICAM1 : toll like receptor adaptor molecule 1

Gene-disease associations table

Disease IDDisease nameSource of annotation with TICAM1OMIM linkNumber of associated genesgenes
PS610551ENCEPHALOPATHY, ACUTE, INFECTION-INDUCEDClinVar, OMIM, HUMSAVAR link to OMIM 7TLR3, CPT2, IRF3, TICAM1, UNC93B1, TRAF3, RANBP2

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Annotation of the gene TICAM1

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Pertussishsa051336.46
Toll-like receptor signaling pathwayhsa046206.0
Chagas disease (American trypanosomiasis)hsa051425.99
Herpes simplex infectionhsa051685.08
Influenza Ahsa051645.21
NF-kappa B signaling pathwayhsa040646.21
Hepatitis Chsa051605.68
Hepatitis Bhsa051615.52
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
TRIF-mediated TLR3/TLR4 signaling R-HSA-9370616.47
IKK complex recruitment mediated by RIP1R-HSA-9370418.46
Toll Like Receptor 4 (TLR4) CascadeR-HSA-1660166.11
TICAM1 deficiency - HSER-HSA-560256611.98
Ligand-dependent caspase activationR-HSA-1405349.08
Programmed Cell DeathR-HSA-53578015.65
DiseaseR-HSA-16436853.33
Toll Like Receptor 3 (TLR3) CascadeR-HSA-1681646.47
Toll-Like Receptors CascadesR-HSA-1688985.91
MyD88-independent TLR3/TLR4 cascade R-HSA-1661666.47
ZBP1(DAI) mediated induction of type I IFNsR-HSA-16063228.28
Caspase activation via extrinsic apoptotic signalig pathwayR-HSA-53577698.34
TRAF6 mediated induction of TAK1 complexR-HSA-9370728.98
Immune SystemR-HSA-1682562.37
TRAF3 deficiency - HSER-HSA-560257111.4
Innate Immune SystemR-HSA-1682493.17
TRIF-mediated programmed cell deathR-HSA-25625789.66
RIP-mediated NFkB activation via ZBP1R-HSA-18104768.59
Cytosolic sensors of pathogen-associated DNA R-HSA-18349496.94
Diseases of Immune SystemR-HSA-52602718.34
Diseases associated with the TLR signaling cascadeR-HSA-56023588.34
Activated TLR4 signallingR-HSA-1660546.27
ApoptosisR-HSA-1095815.68
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilonR-HSA-9369648.81
Associated GO terms for Molecular function
GO termGO IDGO IC
protein bindingGO:00055150.46
enzyme bindingGO:00198992.27
protein kinase bindingGO:00199013.44
kinase bindingGO:00199003.32
bindingGO:00054880.18
signal transducer activityGO:00048712.28