| Disease ID | Disease name | Source of annotation with TNFRSF10B | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 275355 | SQUAMOUS CELL CARCINOMA, HEAD AND NECK | OMIM | link to OMIM | 5 | TNFRSF10B, ING1, PTEN, EGFR, ING3 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Natural killer cell mediated cytotoxicity | hsa04650 | 5.53 |
| p53 signaling pathway | hsa04115 | 6.56 |
| Cytokine-cytokine receptor interaction | hsa04060 | 4.67 |
| Influenza A | hsa05164 | 5.21 |
| Apoptosis | hsa04210 | 6.23 |
| Measles | hsa05162 | 5.6 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Regulation by c-FLIP | R-HSA-3371378 | 9.81 |
| RIPK1-mediated regulated necrosis | R-HSA-5213460 | 8.81 |
| Caspase activation via extrinsic apoptotic signalig pathway | R-HSA-5357769 | 8.34 |
| Regulated Necrosis | R-HSA-5218859 | 8.81 |
| CASP8 activity is inhibited | R-HSA-5218900 | 9.81 |
| Ligand-dependent caspase activation | R-HSA-140534 | 9.08 |
| Programmed Cell Death | R-HSA-5357801 | 5.65 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| Regulation of necroptotic cell death | R-HSA-5675482 | 8.98 |
| Death Receptor Signalling | R-HSA-73887 | 8.52 |
| TRAIL signaling | R-HSA-75158 | 10.18 |
| Dimerization of procaspase-8 | R-HSA-69416 | 9.81 |
| Apoptosis | R-HSA-109581 | 5.68 |
| GO term | GO ID | GO IC |
|---|---|---|
| binding | GO:0005488 | 0.18 |
| signaling receptor activity | GO:0038023 | 2.49 |
| protein binding | GO:0005515 | 0.46 |
| molecular transducer activity | GO:0060089 | 2.32 |
| death receptor activity | GO:0005035 | 6.56 |
| transmembrane signaling receptor activity | GO:0004888 | 2.57 |
| TRAIL binding | GO:0045569 | 8.35 |
| tumor necrosis factor-activated receptor activity | GO:0005031 | 6.56 |
| signal transducer activity | GO:0004871 | 2.28 |
| transmembrane receptor activity | GO:0099600 | 2.53 |
| receptor activity | GO:0004872 | 2.32 |