Gene table of TNFSF11 : tumor necrosis factor superfamily member 11

Gene-disease associations table

Disease IDDisease nameSource of annotation with TNFSF11OMIM linkNumber of associated genesgenes
PS259700OSTEOPETROSIS, AUTOSOMAL RECESSIVEClinVar, OMIM, HUMSAVAR link to OMIM 8TNFRSF11A, TNFSF11, SNX10, PLEKHM1, CA2, CLCN7, OSTM1, TCIRG1

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Annotation of the gene TNFSF11

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Rheumatoid arthritishsa053236.05
NF-kappa B signaling pathwayhsa040646.21
Prolactin signaling pathwayhsa049176.6
Cytokine-cytokine receptor interactionhsa040604.67
Osteoclast differentiationhsa043805.64
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Cytokine Signaling in Immune systemR-HSA-12802153.74
TNFs bind their physiological receptorsR-HSA-56690348.34
TNFR2 non-canonical NF-kB pathwayR-HSA-56685416.4
Immune SystemR-HSA-1682562.37
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathwayR-HSA-56765948.89
Associated GO terms for Molecular function
GO termGO IDGO IC
cytokine receptor bindingGO:00051264.14
tumor necrosis factor receptor superfamily bindingGO:00328135.89
tumor necrosis factor receptor bindingGO:00051646.3
cytokine activityGO:00051254.34
bindingGO:00054880.18
protein bindingGO:00055150.46
receptor bindingGO:00051022.43