Disease ID | Disease name | Source of annotation with TRAF3 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
PS610551 | ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED | ClinVar, OMIM, HUMSAVAR | link to OMIM | 7 | TLR3, CPT2, IRF3, TICAM1, UNC93B1, TRAF3, RANBP2 |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Viral carcinogenesis | hsa05203 | 5.08 |
Toll-like receptor signaling pathway | hsa04620 | 6.0 |
Pathways in cancer | hsa05200 | 3.98 |
RIG-I-like receptor signaling pathway | hsa04622 | 6.62 |
Herpes simplex infection | hsa05168 | 5.08 |
Epstein-Barr virus infection | hsa05169 | 4.97 |
TNF signaling pathway | hsa04668 | 5.96 |
NF-kappa B signaling pathway | hsa04064 | 6.21 |
Hepatitis C | hsa05160 | 5.68 |
Small cell lung cancer | hsa05222 | 6.17 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
TRIF-mediated TLR3/TLR4 signaling | R-HSA-937061 | 6.47 |
Cytokine Signaling in Immune system | R-HSA-1280215 | 3.74 |
TNFR2 non-canonical NF-kB pathway | R-HSA-5668541 | 6.4 |
TRAF3-dependent IRF activation pathway | R-HSA-918233 | 9.18 |
Innate Immune System | R-HSA-168249 | 3.17 |
TRAF3 deficiency - HSE | R-HSA-5602571 | 11.4 |
Toll Like Receptor 4 (TLR4) Cascade | R-HSA-166016 | 6.11 |
Toll Like Receptor 3 (TLR3) Cascade | R-HSA-168164 | 6.47 |
Toll-Like Receptors Cascades | R-HSA-168898 | 5.91 |
Diseases of Immune System | R-HSA-5260271 | 8.34 |
Diseases associated with the TLR signaling cascade | R-HSA-5602358 | 8.34 |
Immune System | R-HSA-168256 | 2.37 |
Negative regulators of RIG-I/MDA5 signaling | R-HSA-936440 | 7.98 |
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway | R-HSA-5676594 | 8.89 |
MyD88-independent TLR3/TLR4 cascade | R-HSA-166166 | 6.47 |
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways | R-HSA-168928 | 6.7 |
Activated TLR4 signalling | R-HSA-166054 | 6.27 |
Disease | R-HSA-1643685 | 3.33 |
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon | R-HSA-936964 | 8.81 |
GO term | GO ID | GO IC |
---|---|---|
cytokine receptor binding | GO:0005126 | 4.14 |
ubiquitin-like protein ligase binding | GO:0044389 | 4.15 |
enzyme binding | GO:0019899 | 2.27 |
binding | GO:0005488 | 0.18 |
signal transducer activity | GO:0004871 | 2.28 |
ubiquitin-like protein transferase activity | GO:0019787 | 3.69 |
cation binding | GO:0043169 | 1.4 |
transition metal ion binding | GO:0046914 | 2.48 |
ligase activity | GO:0016874 | 3.72 |
ion binding | GO:0043167 | 1.36 |
transferase activity | GO:0016740 | 1.95 |
metal ion binding | GO:0046872 | 1.41 |
tumor necrosis factor receptor superfamily binding | GO:0032813 | 5.89 |
protein kinase binding | GO:0019901 | 3.44 |
catalytic activity | GO:0003824 | 1.05 |
protein phosphatase binding | GO:0019903 | 4.93 |
phosphatase binding | GO:0019902 | 4.63 |
tumor necrosis factor receptor binding | GO:0005164 | 6.3 |
ubiquitin-protein transferase activity | GO:0004842 | 3.73 |
ubiquitin protein ligase binding | GO:0031625 | 4.17 |
thioesterase binding | GO:0031996 | 7.25 |
kinase binding | GO:0019900 | 3.32 |
protein binding | GO:0005515 | 0.46 |
receptor binding | GO:0005102 | 2.43 |
zinc ion binding | GO:0008270 | 2.66 |