Gene table of TREM2 : triggering receptor expressed on myeloid cells 2

Gene-disease associations table

Disease IDDisease nameSource of annotation with TREM2OMIM linkNumber of associated genesgenes
221770POLYCYSTIC LIPOMEMBRANOUS OSTEODYSPLASIA WITH SCLEROSING LEUKOENCEPHALOPATHYClinVar, OMIM, HUMSAVAR link to OMIM 2TREM2, TYROBP

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Annotation of the gene TREM2

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Osteoclast differentiationhsa043805.64
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Other semaphorin interactionsR-HSA-4167008.73
Innate Immune SystemR-HSA-1682493.17
Immune SystemR-HSA-1682562.37
DAP12 interactionsR-HSA-21721274.56
DAP12 signalingR-HSA-24244914.64
Semaphorin interactionsR-HSA-3737556.92
Axon guidanceR-HSA-4224753.93
Developmental BiologyR-HSA-12667383.48
Associated GO terms for Molecular function
GO termGO IDGO IC
carbohydrate derivative bindingGO:00973672.03
lipid bindingGO:00082893.26
lipopolysaccharide bindingGO:00015306.69
glycosaminoglycan bindingGO:00055394.42
molecular transducer activityGO:00600892.32
lipoteichoic acid bindingGO:00708918.35
scaffold protein bindingGO:00971105.93
receptor activityGO:00048722.32
protein bindingGO:00055150.46
peptidoglycan bindingGO:00428347.25
bindingGO:00054880.18