Gene table of TUBB1 : tubulin beta 1 class VI

Gene-disease associations table

Disease IDDisease nameSource of annotation with TUBB1OMIM linkNumber of associated genesgenes
613112MACROTHROMBOCYTOPENIA, AUTOSOMAL DOMINANT, TUBB1-RELATEDClinVar, OMIM, HUMSAVAR link to OMIM 1TUBB1

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Annotation of the gene TUBB1

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Pathogenic Escherichia coli infectionhsa051306.99
Phagosomehsa041455.27
Gap junctionhsa045406.24
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Separation of Sister ChromatidsR-HSA-24678135.55
Signaling by HedgehogR-HSA-53583515.79
Immune SystemR-HSA-1682562.37
Signaling by Rho GTPasesR-HSA-1943154.43
Recycling pathway of L1R-HSA-4372397.62
Cell CycleR-HSA-16401703.89
Formation of tubulin folding intermediates by CCT/TriCR-HSA-3899608.66
Gap junction assemblyR-HSA-1908618.03
Microtubule-dependent trafficking of connexons from Golgi to the plasma membraneR-HSA-1908409.28
Assembly of the primary ciliumR-HSA-56178335.44
Adaptive Immune SystemR-HSA-12802183.19
Developmental BiologyR-HSA-12667383.48
Recruitment of mitotic centrosome proteins and complexesR-HSA-3802706.68
Resolution of Sister Chromatid CohesionR-HSA-25002576.18
Hedgehog 'off' stateR-HSA-56107876.19
Mitotic Metaphase and AnaphaseR-HSA-25553965.45
Gap junction traffickingR-HSA-1908287.59
Intraflagellar transportR-HSA-56209247.25
Cell Cycle, MitoticR-HSA-692784.16
Factors involved in megakaryocyte development and platelet productionR-HSA-9832315.88
G2/M TransitionR-HSA-692756.06
RHO GTPases Activate ForminsR-HSA-56632206.01
L1CAM interactionsR-HSA-3737606.19
Cooperation of Prefoldin and TriC/CCT in actin and tubulin foldingR-HSA-3899588.23
Prefoldin mediated transfer of substrate to CCT/TriCR-HSA-3899578.28
Centrosome maturationR-HSA-3802876.68
Mitotic G2-G2/M phasesR-HSA-4532746.04
Metabolism of proteinsR-HSA-3924993.41
Membrane TraffickingR-HSA-1999915.26
M PhaseR-HSA-688864.87
Transport of connexons to the plasma membraneR-HSA-1908729.18
Translocation of GLUT4 to the plasma membraneR-HSA-14451486.77
Mitotic AnaphaseR-HSA-688825.46
Gap junction trafficking and regulationR-HSA-1578587.52
Post-chaperonin tubulin folding pathwayR-HSA-3899778.81
Chaperonin-mediated protein foldingR-HSA-3904667.4
Vesicle-mediated transportR-HSA-56536564.33
RHO GTPase EffectorsR-HSA-1952584.94
Protein foldingR-HSA-3912517.23
Recruitment of NuMA to mitotic centrosomesR-HSA-3803208.46
HemostasisR-HSA-1095823.98
RHO GTPases activate IQGAPsR-HSA-56264678.34
MHC class II antigen presentationR-HSA-21322956.01
Mitotic PrometaphaseR-HSA-688776.08
Axon guidanceR-HSA-4224753.93
KinesinsR-HSA-9831897.7
Organelle biogenesis and maintenanceR-HSA-18522414.63
Signal TransductionR-HSA-1625821.78
Associated GO terms for Molecular function
GO termGO IDGO IC
structural constituent of cytoskeletonGO:00052005.12
purine ribonucleoside triphosphate bindingGO:00356392.22
bindingGO:00054880.18
structural molecule activityGO:00051983.1
heterocyclic compound bindingGO:19013631.06
nucleoside phosphate bindingGO:19012651.96
nucleoside bindingGO:00018822.21
pyrophosphatase activityGO:00164623.04
nucleotide bindingGO:00001661.96
guanyl ribonucleotide bindingGO:00325613.73
purine nucleoside bindingGO:00018832.22
ribonucleoside bindingGO:00325492.22
purine nucleotide bindingGO:00170762.19
GTP bindingGO:00055253.78
hydrolase activityGO:00167871.9
GTPase activityGO:00039244.31
nucleoside-triphosphatase activityGO:00171113.09
small molecule bindingGO:00360941.89
catalytic activityGO:00038241.05
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:00168183.03
carbohydrate derivative bindingGO:00973672.03
organic cyclic compound bindingGO:00971591.05
hydrolase activity, acting on acid anhydridesGO:00168173.03
guanyl nucleotide bindingGO:00190013.73
purine ribonucleotide bindingGO:00325552.2
purine ribonucleoside bindingGO:00325502.22
ribonucleotide bindingGO:00325532.19