| Disease ID | Disease name | Source of annotation with TXN2 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS609060 | COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY | ClinVar, OMIM | link to OMIM | 29 | C12orf65, FARS2, GFM1, TARS2, MTFMT, MTO1, AIFM1, EARS2, NARS2, SFXN4, MRPS22, PNPT1, TSFM, ATP5A1, LYRM4, SLC25A26, MRPS16, MRPL3, TUFM, TRMT5, MRPL44, GTPBP3, VARS2, CARS2, RMND1, ELAC2, AARS2, TXN2, MARS2 |
Download the gene annotation in CSV format
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 8.23 |
| Cellular responses to stress | R-HSA-2262752 | 4.56 |
| GO term | GO ID | GO IC |
|---|---|---|
| peptide-methionine (R)-S-oxide reductase activity | GO:0033743 | 8.35 |
| peptide-methionine (S)-S-oxide reductase activity | GO:0008113 | 9.05 |
| oxidoreductase activity, acting on a sulfur group of donors | GO:0016667 | 5.83 |
| catalytic activity | GO:0003824 | 1.05 |
| oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor | GO:0016671 | 7.17 |
| macromolecular complex binding | GO:0044877 | 2.61 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| protein complex binding | GO:0032403 | 3.09 |
| oxidoreductase activity | GO:0016491 | 3.12 |
| protein disulfide oxidoreductase activity | GO:0015035 | 6.56 |
| disulfide oxidoreductase activity | GO:0015036 | 6.3 |