Disease ID | Disease name | Source of annotation with TYROBP | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
221770 | POLYCYSTIC LIPOMEMBRANOUS OSTEODYSPLASIA WITH SCLEROSING LEUKOENCEPHALOPATHY | ClinVar, OMIM | link to OMIM | 2 | TREM2, TYROBP |
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KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Natural killer cell mediated cytotoxicity | hsa04650 | 5.53 |
Osteoclast differentiation | hsa04380 | 5.64 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Other semaphorin interactions | R-HSA-416700 | 8.73 |
Innate Immune System | R-HSA-168249 | 3.17 |
Immune System | R-HSA-168256 | 2.37 |
Cell-Cell communication | R-HSA-1500931 | 5.87 |
DAP12 interactions | R-HSA-2172127 | 4.56 |
DAP12 signaling | R-HSA-2424491 | 4.64 |
Semaphorin interactions | R-HSA-373755 | 6.92 |
Axon guidance | R-HSA-422475 | 3.93 |
Signal regulatory protein (SIRP) family interactions | R-HSA-391160 | 8.98 |
Adaptive Immune System | R-HSA-1280218 | 3.19 |
Developmental Biology | R-HSA-1266738 | 3.48 |
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | R-HSA-198933 | 4.7 |
GO term | GO ID | GO IC |
---|---|---|
protein binding | GO:0005515 | 0.46 |
receptor signaling protein activity | GO:0005057 | 4.76 |
binding | GO:0005488 | 0.18 |
signal transducer activity | GO:0004871 | 2.28 |
receptor binding | GO:0005102 | 2.43 |
identical protein binding | GO:0042802 | 2.63 |