| Disease ID | Disease name | Source of annotation with UNG | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS308230 | IMMUNODEFICIENCY WITH HYPER-IGM | ClinVar, OMIM, HUMSAVAR | link to OMIM | 4 | AICDA, CD40LG, UNG, CD40 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Primary immunodeficiency | hsa05340 | 7.52 |
| Base excision repair | hsa03410 | 7.6 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Displacement of DNA glycosylase by APEX1 | R-HSA-110357 | 9.81 |
| Cleavage of the damaged pyrimidine | R-HSA-110329 | 9.98 |
| Recognition and association of DNA glycosylase with site containing an affected pyrimidine | R-HSA-110328 | 9.98 |
| Resolution of Abasic Sites (AP sites) | R-HSA-73933 | 7.85 |
| DNA Repair | R-HSA-73894 | 5.8 |
| Base Excision Repair | R-HSA-73884 | 7.85 |
| Depyrimidination | R-HSA-73928 | 9.98 |
| Base-Excision Repair, AP Site Formation | R-HSA-73929 | 9.66 |
| GO term | GO ID | GO IC |
|---|---|---|
| hydrolase activity | GO:0016787 | 1.9 |
| protein binding | GO:0005515 | 0.46 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| DNA N-glycosylase activity | GO:0019104 | 7.03 |
| hydrolase activity, hydrolyzing N-glycosyl compounds | GO:0016799 | 6.6 |
| hydrolase activity, acting on glycosyl bonds | GO:0016798 | 4.91 |
| enzyme binding | GO:0019899 | 2.27 |
| heterocyclic compound binding | GO:1901363 | 1.06 |
| catalytic activity | GO:0003824 | 1.05 |
| deaminated base DNA N-glycosylase activity | GO:0097506 | 8.13 |
| binding | GO:0005488 | 0.18 |
| nucleic acid binding | GO:0003676 | 1.44 |
| DNA binding | GO:0003677 | 1.92 |
| uracil DNA N-glycosylase activity | GO:0004844 | 8.13 |
| damaged DNA binding | GO:0003684 | 5.58 |