| Rho guanyl-nucleotide exchange factor activity | GO:0005089 | 5.37 |
| Ras guanyl-nucleotide exchange factor activity | GO:0005088 | 4.31 |
| guanyl-nucleotide exchange factor activity | GO:0005085 | 4.02 |
| binding | GO:0005488 | 0.18 |
| molecular function regulator | GO:0098772 | 2.51 |
| SH3/SH2 adaptor activity | GO:0005070 | 5.79 |
| cation binding | GO:0043169 | 1.4 |
| ion binding | GO:0043167 | 1.36 |
| metal ion binding | GO:0046872 | 1.41 |
| epidermal growth factor receptor binding | GO:0005154 | 6.34 |
| enzyme regulator activity | GO:0030234 | 2.85 |
| GTPase activator activity | GO:0005096 | 4.11 |
| GTPase regulator activity | GO:0030695 | 4.01 |
| nucleoside-triphosphatase regulator activity | GO:0060589 | 3.92 |
| binding, bridging | GO:0060090 | 4.57 |
| Rac guanyl-nucleotide exchange factor activity | GO:0030676 | 7.17 |
| protein binding, bridging | GO:0030674 | 4.68 |
| growth factor receptor binding | GO:0070851 | 4.87 |
| signaling adaptor activity | GO:0035591 | 5.43 |
| protein binding | GO:0005515 | 0.46 |
| receptor binding | GO:0005102 | 2.43 |
| enzyme activator activity | GO:0008047 | 3.56 |