Gene table of WHSC1L1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with WHSC1L1	OMIM link	Number of associated genes	genes
601626	LEUKEMIA, ACUTE MYELOID	OMIM	link to OMIM	23	FLT3, RUNX1, WHSC1L1, KIT, MLF1, CHIC2, CEBPA, LPP, SH3GL1, PICALM, NPM1, CBFB, ETV6, SETBP1, MLLT10, TERT, NUP214, JAK2, GATA2, TGM6, DDX41, NSD1, KRAS

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Lysine degradation	hsa00310	7.01

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Chromatin organization	R-HSA-4839726	5.19
PKMTs methylate histone lysines	R-HSA-3214841	7.66
Chromatin modifying enzymes	R-HSA-3247509	5.19

Associated GO terms for Molecular function

GO term	GO ID	GO IC
histone-lysine N-methyltransferase activity	GO:0018024	5.93
histone methyltransferase activity	GO:0042054	5.68
transition metal ion binding	GO:0046914	2.48
metal ion binding	GO:0046872	1.41
S-adenosylmethionine-dependent methyltransferase activity	GO:0008757	4.81
cation binding	GO:0043169	1.4
lysine N-methyltransferase activity	GO:0016278	5.7
protein-lysine N-methyltransferase activity	GO:0016279	5.71
protein methyltransferase activity	GO:0008276	5.33
catalytic activity	GO:0003824	1.05
transferase activity	GO:0016740	1.95
transferase activity, transferring one-carbon groups	GO:0016741	4.3
N-methyltransferase activity	GO:0008170	5.26
binding	GO:0005488	0.18
protein binding	GO:0005515	0.46
methyltransferase activity	GO:0008168	4.35
ion binding	GO:0043167	1.36
zinc ion binding	GO:0008270	2.66