| Disease ID | Disease name | Source of annotation with WNT7A | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 228930 | FIBULAR APLASIA OR HYPOPLASIA, FEMORAL BOWING AND POLY-, SYN-, AND OLIGODACTYLY | OMIM, HUMSAVAR | link to OMIM | 1 | WNT7A |
| 276820 | ULNA AND FIBULA, ABSENCE OF, WITH SEVERE LIMB DEFICIENCY | ClinVar, OMIM, HUMSAVAR | link to OMIM | 1 | WNT7A |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Signaling pathways regulating pluripotency of stem cells | hsa04550 | 5.6 |
| Hedgehog signaling pathway | hsa04340 | 7.01 |
| Proteoglycans in cancer | hsa05205 | 5.02 |
| Pathways in cancer | hsa05200 | 3.98 |
| Basal cell carcinoma | hsa05217 | 6.79 |
| Melanogenesis | hsa04916 | 5.97 |
| Hippo signaling pathway | hsa04390 | 5.37 |
| HTLV-I infection | hsa05166 | 4.59 |
| Wnt signaling pathway | hsa04310 | 5.49 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Class B/2 (Secretin family receptors) | R-HSA-373080 | 6.52 |
| Signaling by Wnt | R-HSA-195721 | 4.79 |
| Signaling by GPCR | R-HSA-372790 | 2.68 |
| WNT ligand biogenesis and trafficking | R-HSA-3238698 | 8.28 |
| GPCR ligand binding | R-HSA-500792 | 4.19 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| GO term | GO ID | GO IC |
|---|---|---|
| cytokine activity | GO:0005125 | 4.34 |
| protein binding | GO:0005515 | 0.46 |
| frizzled binding | GO:0005109 | 6.1 |
| receptor regulator activity | GO:0030545 | 5.91 |
| receptor activator activity | GO:0030546 | 6.27 |
| receptor agonist activity | GO:0048018 | 6.97 |
| binding | GO:0005488 | 0.18 |
| signal transducer activity | GO:0004871 | 2.28 |
| G-protein coupled receptor binding | GO:0001664 | 4.18 |
| receptor binding | GO:0005102 | 2.43 |
| molecular function regulator | GO:0098772 | 2.51 |