Gene table of WT1 : Wilms tumor 1

Gene-disease associations table

Disease IDDisease nameSource of annotation with WT1OMIM linkNumber of associated genesgenes
194080DENYS-DRASH SYNDROMEClinVar, OMIM, HUMSAVAR link to OMIM 1WT1
PS256300NEPHROTIC SYNDROMEClinVar, OMIM, HUMSAVAR link to OMIM 14LAMB2, NUP93, NUP205, NPHS1, OPA1, NPHS2, ADCK4, NUP107, WT1, ARHGDIA, PTPRO, PLCE1, EMP2, DGKE
PS194070WILMS TUMORClinVar, OMIM, HUMSAVAR link to OMIM 6WT1, REST, H19, GPC3, BRCA2, POU6F2
608978MEACHAM SYNDROMEOMIM, HUMSAVAR link to OMIM 1WT1
136680FRASIER SYNDROMEOMIM, HUMSAVAR link to OMIM 1WT1
156240MESOTHELIOMA, MALIGNANTOMIM link to OMIM 2WT1, BCL10

Download the gene annotation in CSV format

Annotation of the gene WT1

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is a TF of the genes:

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Transcriptional misregulation in cancerhsa052025.21
Associated REACTOME pathways
Associated GO terms for Molecular function
GO termGO IDGO IC
bindingGO:00054880.18
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingGO:00010774.31
zinc ion bindingGO:00082702.66
nucleic acid bindingGO:00036761.44
DNA bindingGO:00036771.92
heterocyclic compound bindingGO:19013631.06
sequence-specific DNA bindingGO:00435652.79
transition metal ion bindingGO:00469142.48
ion bindingGO:00431671.36
C2H2 zinc finger domain bindingGO:00707427.1
metal ion bindingGO:00468721.41
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific bindingGO:00009823.94
RNA polymerase II transcription factor activity, sequence-specific DNA bindingGO:00009813.29
cation bindingGO:00431691.4
regulatory region nucleic acid bindingGO:00010673.03
protein domain specific bindingGO:00199043.32
transcription regulatory region DNA bindingGO:00442123.03
transcription factor activity, sequence-specific DNA bindingGO:00037002.65
organic cyclic compound bindingGO:00971591.05
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific bindingGO:00012283.98
RNA bindingGO:00037232.36
protein bindingGO:00055150.46
regulatory region DNA bindingGO:00009753.03
nucleic acid binding transcription factor activityGO:00010712.65